PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33953730-3	2021	PIP3 is subject to dephosphorylation by several 5" phosphatases, including SHIP family phosphatases, which convert the PI3K product and lipid second messenger phosphatidylinositol 3,4,5-trisphosphate (PIP3) into PI(3,4)P2, a lipid second messenger in its own right.	PIP3	0-4	inositol polyphosphate-5-phosphatase D	Homo sapiens	75-79	
10942391-3	2000	Because SHIP dephosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3) and activation of Akt requires PIP3, the destruction of this phospholipid has been proposed as the mechanism for Akt inhibition.	PIP3	72-76	inositol polyphosphate-5-phosphatase D	Homo sapiens	8-12	
10066815-3	1999	In vitro, SHIP catalyzes the conversion of the phosphoinositide 3-kinase (PI3K) product phosphatidylinositol 3,4, 5-trisphosphate (PIP3) into phosphatidylinositol 3,4-bisphosphate.	PIP3	131-135	inositol polyphosphate-5-phosphatase D	Homo sapiens	10-14	
9857188-7	1998	These results suggest that SHIP prevents SF from triggering degranulation of normal BMMCs, and does so by hydrolyzing PIP3, which in turn limits extracellular calcium entry at a step after the release of intracellular calcium.	PIP3	118-122	inositol polyphosphate-5-phosphatase D	Homo sapiens	27-31	
33953730-3	2021	PIP3 is subject to dephosphorylation by several 5" phosphatases, including SHIP family phosphatases, which convert the PI3K product and lipid second messenger phosphatidylinositol 3,4,5-trisphosphate (PIP3) into PI(3,4)P2, a lipid second messenger in its own right.	PIP3	201-205	inositol polyphosphate-5-phosphatase D	Homo sapiens	75-79	
29925063-5	2018	SHIP is another inhibitory phosphatase that is specific for the inositol phospholipid phosphatidylinositol-3,4,5-trisphosphate (PIP3).	PIP3	128-132	inositol polyphosphate-5-phosphatase D	Homo sapiens	0-4	
29681901-5	2018	In this context, Lyn appears to function primarily as a driver of inhibitory signaling pathways promoting the inhibition of the PI3K pathway by inositol phosphatases, SHIP-1 and PTEN, which hydrolyze PIP3 to PIP2.	PIP3	200-204	inositol polyphosphate-5-phosphatase D	Homo sapiens	167-173