PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27393926-5	2016	Furthermore, the level of beta-endorphin in the plasma and the expression of beta-endorphin, mu-opioid receptor, and macrophages in the dorsal skin increased after the administration of tranexamic acid, and this increase was higher in female mice than in males.	Tranexamic Acid	186-201	pro-opiomelanocortin-alpha	Mus musculus	26-40	
30081203-6	2018	Conversely, the levels of beta-endorphin and mu-opioid receptor increased with tranexamic acid treatment.	Tranexamic Acid	79-94	pro-opiomelanocortin-alpha	Mus musculus	26-40	
27393926-5	2016	Furthermore, the level of beta-endorphin in the plasma and the expression of beta-endorphin, mu-opioid receptor, and macrophages in the dorsal skin increased after the administration of tranexamic acid, and this increase was higher in female mice than in males.	Tranexamic Acid	186-201	pro-opiomelanocortin-alpha	Mus musculus	77-91	
27133035-6	2016	Moreover, the increase in the beta-endorphin level in the blood and the expression of mu-opioid receptor on the surface of fibroblasts increased by tranexamic acid treatment.	Tranexamic Acid	148-163	pro-opiomelanocortin-alpha	Mus musculus	30-44	
26663237-7	2016	Following the administration of tranexamic acid, the female displayed increased blood levels of beta-endorphin and mu-opioid receptor and estradiol receptor beta expression in comparison with the male.	Tranexamic Acid	32-47	pro-opiomelanocortin-alpha	Mus musculus	96-110	
26663237-9	2016	CONCLUSIONS: These results suggest that the suppression by tranexamic acid of the UVB-induced melanocyte activation (UVB sensitivity) is stronger in female mice than in male mice and that female hormones and beta-endorphin play an important role in this sex difference.	Tranexamic Acid	59-74	pro-opiomelanocortin-alpha	Mus musculus	208-222