PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10570059-8 1999 Increased survival of topo IIbeta -/- cells compared with topo IIbeta +/+ cells was observed after treatment with amsacrine (mAMSA), methyl N-(4"-[9-acridinylamino]-2-methoxyphenyl) carbamate hydrochloride (AMCA), methyl N-(4"-[9-acridinylamino]-2-methoxyphenyl)carbamate hydrochloride (mAMCA), mitoxantrone, and etoposide. Tranexamic Acid 207-211 ATPase, class II, type 9B Mus musculus 27-33 10570059-9 1999 These studies showed that topo IIbeta -/- cells were significantly more resistant to mAMSA, AMCA, mAMCA, and mitoxantrone, than topo IIbeta +/+ cells, indicating that topo IIbeta is an important target for the cytotoxic effects of these compounds. Tranexamic Acid 92-96 ATPase, class II, type 9B Mus musculus 31-37