PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17137520-0	2006	Berberine chloride can ameliorate the spatial memory impairment and increase the expression of interleukin-1beta and inducible nitric oxide synthase in the rat model of Alzheimer"s disease.	berberine chloride	0-18	interleukin 1 beta	Rattus norvegicus	95-112	
18357892-0	2008	[Effect of berberine hydrochloride on the expression of interleukin-1beta and tumor necrosis factor-alpha in periodontal tissues in rats].	berberine chloride	11-34	interleukin 1 beta	Rattus norvegicus	56-73	
18357892-1	2008	OBJECTIVE: To determine the effects of berberine hydrochloride on the expressions of interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) in periodontal tissues in rat periodontitis model.	berberine chloride	39-62	interleukin 1 beta	Rattus norvegicus	85-102	
18357892-1	2008	OBJECTIVE: To determine the effects of berberine hydrochloride on the expressions of interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) in periodontal tissues in rat periodontitis model.	berberine chloride	39-62	interleukin 1 beta	Rattus norvegicus	104-112	
18357892-6	2008	Treatment with berberine hydrochloride decreased the levels of IL-1beta and TNF-alpha in periodontitis tissues (P<0.05).	berberine chloride	15-38	interleukin 1 beta	Rattus norvegicus	63-71	
18357892-8	2008	CONCLUSION: Berberine hydrochloride inhibited the expression of IL-1beta and TNF-alpha in periodontal tissues in rats periodontitis model and promoted the regeneration of the periodontal tissues.	berberine chloride	12-35	interleukin 1 beta	Rattus norvegicus	64-72	
17137520-3	2006	The present study was carried out to investigate the effect of berberine chloride on the spatial memory, inflammation factors interleukin-1 beta (IL-1beta) and inducible nitric oxide synthase (iNOS) expression in the rat model of Alzheimer"s disease (AD) which was established by injecting Abeta (1-40) (5 microgram) into the rats hippocampuses bilaterally.	berberine chloride	63-81	interleukin 1 beta	Rattus norvegicus	126-144