PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29725453-6	2018	Berberine hydrochloride treatment inhibited the expression of vascular endothelial growth factor (VEGF) and nuclear factor kappaB (NF-kappaB) and transcription factor AP-1 (AP-1) proteins, in A549 cells.	berberine chloride	0-23	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	167-171	
29725453-6	2018	Berberine hydrochloride treatment inhibited the expression of vascular endothelial growth factor (VEGF) and nuclear factor kappaB (NF-kappaB) and transcription factor AP-1 (AP-1) proteins, in A549 cells.	berberine chloride	0-23	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	173-177	
29725453-8	2018	Subsequently, treatment with berberine hydrochloride significantly downregulated MMP-2 protein expression, increased the activity of the Bcl-2/Bax signaling pathway and suppressed the Jak2/VEGF/NF-kappaB/AP-1signaling pathways.	berberine chloride	29-52	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	204-208	
29725453-9	2018	These results suggest that berberine hydrochloride may be a potential novel anticancer drug, since it inhibits cell proliferation and promotes the rate of apoptosis of NSCLC cells by the suppression of the MMP-2, Bcl-2/Bax and Jak2/VEGF/NF-kappaB/AP-1 signaling pathways.	berberine chloride	27-50	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	247-251