PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29725453-0	2018	Berberine hydrochloride inhibits cell proliferation and promotes apoptosis of non-small cell lung cancer via the suppression of the MMP2 and Bcl-2/Bax signaling pathways.	berberine chloride	0-23	matrix metallopeptidase 2	Homo sapiens	132-136	
29725453-3	2018	The present study aimed to determine the possible anticancer effects of berberine hydrochloride treatment on human non-small cell lung cancer (NSCLC) cell proliferation and apoptosis via the matrix metalloproteinase 2 (MMP-2) and the B-cell lymphoma 2 (Bcl-2)/Bcl-2-associated X protein (Bax) signaling pathway.	berberine chloride	72-95	matrix metallopeptidase 2	Homo sapiens	191-217	
29725453-3	2018	The present study aimed to determine the possible anticancer effects of berberine hydrochloride treatment on human non-small cell lung cancer (NSCLC) cell proliferation and apoptosis via the matrix metalloproteinase 2 (MMP-2) and the B-cell lymphoma 2 (Bcl-2)/Bcl-2-associated X protein (Bax) signaling pathway.	berberine chloride	72-95	matrix metallopeptidase 2	Homo sapiens	219-224	
29725453-8	2018	Subsequently, treatment with berberine hydrochloride significantly downregulated MMP-2 protein expression, increased the activity of the Bcl-2/Bax signaling pathway and suppressed the Jak2/VEGF/NF-kappaB/AP-1signaling pathways.	berberine chloride	29-52	matrix metallopeptidase 2	Homo sapiens	81-86	
29725453-9	2018	These results suggest that berberine hydrochloride may be a potential novel anticancer drug, since it inhibits cell proliferation and promotes the rate of apoptosis of NSCLC cells by the suppression of the MMP-2, Bcl-2/Bax and Jak2/VEGF/NF-kappaB/AP-1 signaling pathways.	berberine chloride	27-50	matrix metallopeptidase 2	Homo sapiens	206-211