PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23461011-3 2013 Acetylcholinesterase reactivation peak (5-mins long) was found to take place upon introduction of dipyroxime (32.5%), pralidoxime (18%), carboxyme (16%) at a concentration of 2.5 x 10(-4) mol/l or toxogonine (26%) at a concentration of 5 x 10(-4) mol/l. OBIDOXIME CHLORIDE 197-207 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 10433700-2 1999 This study with native, wild-type, and mutant recombinant DNA-expressed AChEs, each inhibited by representative OP compounds, establishes a relationship between edrophonium acceleration of oxime-induced reactivation of OP-AChE conjugates and phosphoryl oxime inhibition of the reactivated enzyme that occurs during reactivation by pyridinium oximes LuH6 and TMB4. OBIDOXIME CHLORIDE 349-353 acetylcholinesterase (Cartwright blood group) Homo sapiens 72-76 10433700-4 1999 Phosphoryl oximes formed during reactivation of the ethoxy methylphosphonyl-AChE conjugate by LuH6 and TMB4 were isolated for the first time and their structures confirmed by (31)P NMR. OBIDOXIME CHLORIDE 94-98 acetylcholinesterase (Cartwright blood group) Homo sapiens 76-80 10433700-6 1999 The purified ethoxy methylphosphonyl oximes formed during the reactivation of ethoxy methylphosphonyl-AChE conjugate with LuH6 and TMB4 are 10- to 22-fold more potent than MEPQ as inhibitors of AChE and stable for several hours at pH 7.2 in HEPES buffer. OBIDOXIME CHLORIDE 122-126 acetylcholinesterase (Cartwright blood group) Homo sapiens 102-106 10433700-6 1999 The purified ethoxy methylphosphonyl oximes formed during the reactivation of ethoxy methylphosphonyl-AChE conjugate with LuH6 and TMB4 are 10- to 22-fold more potent than MEPQ as inhibitors of AChE and stable for several hours at pH 7.2 in HEPES buffer. OBIDOXIME CHLORIDE 122-126 acetylcholinesterase (Cartwright blood group) Homo sapiens 194-198 10433700-8 1999 Our results emphasize that certain oximes, such as LuH6 and TMB4, if used in the treatment of OP pesticide poisoning may cause prolonged inhibition of AChE due to formation of phosphoryl oximes. OBIDOXIME CHLORIDE 51-55 acetylcholinesterase (Cartwright blood group) Homo sapiens 151-155