PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10918503-6 2000 Upon activation of E2F1 by the ligand 4-hydroxy-tamoxifen (4-OHT) the ER-E2F1 fusion protein correctly translocated from the cytosol to the nucleus, transactivated E2F-dependent promoters, and rapidly induced substantial E2F1-related toxicity. 4'-hydroxytamoxifen 38-57 E2F transcription factor 1 Homo sapiens 19-23 10918503-6 2000 Upon activation of E2F1 by the ligand 4-hydroxy-tamoxifen (4-OHT) the ER-E2F1 fusion protein correctly translocated from the cytosol to the nucleus, transactivated E2F-dependent promoters, and rapidly induced substantial E2F1-related toxicity. 4'-hydroxytamoxifen 38-57 E2F transcription factor 1 Homo sapiens 73-77 10918503-6 2000 Upon activation of E2F1 by the ligand 4-hydroxy-tamoxifen (4-OHT) the ER-E2F1 fusion protein correctly translocated from the cytosol to the nucleus, transactivated E2F-dependent promoters, and rapidly induced substantial E2F1-related toxicity. 4'-hydroxytamoxifen 38-57 E2F transcription factor 1 Homo sapiens 73-77