PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11777983-7	2002	EMSAs demonstrated that IL-17, IL-1beta, and TNF-alpha induced NF-kappaB activation within 1.5 h after stimulation, and a blockade of NF-kappaB activation by the pyrrolidine derivative of dithiocarbamate and tosyl-phe-chloromethylketone markedly reduced the IL-17-, IL-1beta-, or TNF-alpha-induced IL-6 gene expression.	Dithiocarbamate	188-203	nuclear factor kappa B subunit 1	Homo sapiens	63-72	
8158536-7	1994	This immediate early response could be mitigated utilizing H7, Calmodulin, or PDTC (a pyrrolidone derivative of dithiocarbamate), suggesting that the pathway was protein kinase-dependent and that the NF-kappa B site may be involved.	Dithiocarbamate	112-127	nuclear factor kappa B subunit 1	Homo sapiens	200-210	
24760275-17	2014	The phosphorylation levels of p65 were significantly decreased in Huh-7 and Hep3B cells after treatment with the Akt signaling inhibitor LY294002 and EP4R agonist for 24 h. Treatment with the NF-kappaB inhibitor pyrrolidine dithiocarbamate (PDTC) at 10 muM for 24 h blocked EP4R-agonist-induced Snail upregulation in Huh-7 and Hep3B cells.	Dithiocarbamate	224-239	nuclear factor kappa B subunit 1	Homo sapiens	192-201	
17979756-0	2007	Targeting of nuclear factor-kappaB and proteasome by dithiocarbamate complexes with metals.	Dithiocarbamate	53-68	nuclear factor kappa B subunit 1	Homo sapiens	13-34	
17979756-9	2007	This review focuses on the biological activity of dithiocarbamate coordination compounds with regard to their possible molecular targets in NF-kappaB signaling and proteasome (JAMM domain proteins).	Dithiocarbamate	50-65	nuclear factor kappa B subunit 1	Homo sapiens	140-149	
11777983-7	2002	EMSAs demonstrated that IL-17, IL-1beta, and TNF-alpha induced NF-kappaB activation within 1.5 h after stimulation, and a blockade of NF-kappaB activation by the pyrrolidine derivative of dithiocarbamate and tosyl-phe-chloromethylketone markedly reduced the IL-17-, IL-1beta-, or TNF-alpha-induced IL-6 gene expression.	Dithiocarbamate	188-203	nuclear factor kappa B subunit 1	Homo sapiens	134-143	
8558060-9	1996	The pyrrolidine derivative of dithiocarbamate, a potent inhibitor of nuclear factor-kappa B (NF-kappa B) activation, resulted in a marked reduction in collagenase gene transcription, however, no reduction of TNF-alpha secretion was noted.	Dithiocarbamate	30-45	nuclear factor kappa B subunit 1	Homo sapiens	93-103	
8558060-9	1996	The pyrrolidine derivative of dithiocarbamate, a potent inhibitor of nuclear factor-kappa B (NF-kappa B) activation, resulted in a marked reduction in collagenase gene transcription, however, no reduction of TNF-alpha secretion was noted.	Dithiocarbamate	30-45	nuclear factor kappa B subunit 1	Homo sapiens	69-91