PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3128168-4 1988 Nordihydroguaiaretic acid (NDGA), eicosatetraynoic acid (ETYA), and indomethacin, extensively utilized inhibitors of the cyclooxygenase and lipoxygenase branches of the arachidonate cascade, also inhibit cytochrome P-450-dependent arachidonic acid metabolism. Masoprocol 0-25 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 204-220 8843902-12 1996 The inhibitory effect of AngII was abolished completely by losartan (0.1 microM), a specific antagonist of the AT1 receptor-subtype of AngII, and by nordihydroguaiaretic acid (50 microM), which at this concentration inhibits the lipoxygenase and cytochrome P-450-dependent pathways of arachidonic acid metabolism. Masoprocol 149-174 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 246-262 8021298-7 1994 In cells treated with nordihydroguaiaretic acid (NDGA), clotramizole, or econazole, compounds with lipoxygenase and cytochrome P-450 inhibitory actions, the thapsigargin-induced entry of calcium was decreased in a dose-dependent manner. Masoprocol 22-47 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 116-132 8021298-7 1994 In cells treated with nordihydroguaiaretic acid (NDGA), clotramizole, or econazole, compounds with lipoxygenase and cytochrome P-450 inhibitory actions, the thapsigargin-induced entry of calcium was decreased in a dose-dependent manner. Masoprocol 49-53 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 116-132 1680628-0 1991 Nordihydroguaiaretic acid, an inhibitor of lipoxygenase, also inhibits cytochrome P-450-mediated monooxygenase activity in rat epidermal and hepatic microsomes. Masoprocol 0-25 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 71-87 1680628-2 1991 In this study, we investigated the effect of NDGA on rat epidermal and hepatic monooxygenase activity and its interaction with rat hepatic microsomal cytochrome P-450. Masoprocol 45-49 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 150-166