PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22348441-2 2012 This study investigated their effect on the metabolism and pharmacokinetics of sulfasalazine (SSZ), a drug whose efficacy depends on metabolism by azoreductase (AR) in the gut microbiota to sulfapyridine (SP) and 5-acetylsalicylic acid (5-ASA). 5-Aminosalicylic acid 237-242 NAD(P)H quinone dehydrogenase 1 Rattus norvegicus 161-163