PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23462851-11 2013 The long amplicon-quantitative PCR assay quantified significantly higher levels of oxidative DNA damage in hypoxanthine phosphoribosyltransferase 1 (HPRT) and polymerase beta (POLB) genes of cultured human cells exposed to chronic THS for 24h compared with untreated cells, suggesting that THS exposure is related to increased oxidative stress and could be an important contributing factor in THS-mediated toxicity. THYMIDINE-5'-(DITHIO)PHOSPHATE 231-234 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 107-147 23462851-11 2013 The long amplicon-quantitative PCR assay quantified significantly higher levels of oxidative DNA damage in hypoxanthine phosphoribosyltransferase 1 (HPRT) and polymerase beta (POLB) genes of cultured human cells exposed to chronic THS for 24h compared with untreated cells, suggesting that THS exposure is related to increased oxidative stress and could be an important contributing factor in THS-mediated toxicity. THYMIDINE-5'-(DITHIO)PHOSPHATE 231-234 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 149-153 23462851-11 2013 The long amplicon-quantitative PCR assay quantified significantly higher levels of oxidative DNA damage in hypoxanthine phosphoribosyltransferase 1 (HPRT) and polymerase beta (POLB) genes of cultured human cells exposed to chronic THS for 24h compared with untreated cells, suggesting that THS exposure is related to increased oxidative stress and could be an important contributing factor in THS-mediated toxicity. THYMIDINE-5'-(DITHIO)PHOSPHATE 290-293 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 149-153 23462851-11 2013 The long amplicon-quantitative PCR assay quantified significantly higher levels of oxidative DNA damage in hypoxanthine phosphoribosyltransferase 1 (HPRT) and polymerase beta (POLB) genes of cultured human cells exposed to chronic THS for 24h compared with untreated cells, suggesting that THS exposure is related to increased oxidative stress and could be an important contributing factor in THS-mediated toxicity. THYMIDINE-5'-(DITHIO)PHOSPHATE 290-293 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 149-153