PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18315550-7 2008 The crystal structure of thrombin in complex with FM19 shows that the N-terminal D-Arg retrobinds into the S1 pocket, its second residue Oic interacts with His-57, Tyr-60a and Trp-60d, and its C-terminal p-methyl Phe engages thrombin"s aryl binding site composed of Ile-174, Trp-215, and Leu-99. D-Arginine 81-86 coagulation factor II Mus musculus 25-33