PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25747030-9	2014	Metal-on-metal implant failure has disclosed that quite like Ni(2+), its neighbor in the periodic table Co(2+) can directly activate toll-like receptor 4 (TLR4) as a lipopolysaccharide-mimic.	Nickel(2+)	61-67	toll like receptor 4	Homo sapiens	133-153	
28965571-0	2017	Ni(II) interaction with a peptide model of the human TLR4 ectodomain.	Nickel(2+)	0-6	toll like receptor 4	Homo sapiens	53-57	
28965571-1	2017	Ni(II) stimulates innate immunity via the direct binding to human Toll Like Receptor 4 (hTLR4), the bacterial lypopolysaccharide receptor.	Nickel(2+)	0-6	toll like receptor 4	Homo sapiens	66-86	
28965571-1	2017	Ni(II) stimulates innate immunity via the direct binding to human Toll Like Receptor 4 (hTLR4), the bacterial lypopolysaccharide receptor.	Nickel(2+)	0-6	toll like receptor 4	Homo sapiens	88-93	
24169691-0	2014	Ni(II) binding to the 429-460 peptide fragment from human Toll like receptor (hTLR4): a crucial role for nickel-induced contact allergy?	Nickel(2+)	0-6	toll like receptor 4	Homo sapiens	78-83	
25747030-9	2014	Metal-on-metal implant failure has disclosed that quite like Ni(2+), its neighbor in the periodic table Co(2+) can directly activate toll-like receptor 4 (TLR4) as a lipopolysaccharide-mimic.	Nickel(2+)	61-67	toll like receptor 4	Homo sapiens	155-159	
23059983-2	2012	Ni(2+) stimulates innate immunity via TLR4/MD2, the bacterial LPS receptor.	Nickel(2+)	0-6	toll like receptor 4	Homo sapiens	38-42	
20711192-3	2010	Here we show that Ni(2+) triggered an inflammatory response by directly activating human Toll-like receptor 4 (TLR4).	Nickel(2+)	18-24	toll like receptor 4	Homo sapiens	89-109	
20711192-3	2010	Here we show that Ni(2+) triggered an inflammatory response by directly activating human Toll-like receptor 4 (TLR4).	Nickel(2+)	18-24	toll like receptor 4	Homo sapiens	111-115	
20711192-6	2010	Accordingly, transgenic expression of human TLR4 in TLR4-deficient mice allowed efficient sensitization to Ni(2+) and elicitation of CHS.	Nickel(2+)	107-113	toll like receptor 4	Homo sapiens	44-48