PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9459494-6	1997	We demonstrated that treatment of HUVEC with Ni2+ and Co2+ ions induces the translocation of NF-kappaB p65 and also p50 into the nucleus.	Nickel(2+)	45-49	nuclear factor kappa B subunit 1	Homo sapiens	116-119	
9459494-6	1997	We demonstrated that treatment of HUVEC with Ni2+ and Co2+ ions induces the translocation of NF-kappaB p65 and also p50 into the nucleus.	Nickel(2+)	45-49	nuclear factor kappa B subunit 1	Homo sapiens	93-102	
25069803-3	2014	Ni(II)-induced toxicogenomic change has been associated with altered activity of HIF, p53, c-MYC, NFkappaB and iron and 2-oxoglutarate-dependent dioxygenases.	Nickel(2+)	0-6	nuclear factor kappa B subunit 1	Homo sapiens	98-106	
25069803-4	2014	Advancing high-throughput technology has indicated the toxicogenome of Ni(II) involves crosstalk between HIF, p53, c-MYC, NFkappaB and dioxygenases.	Nickel(2+)	71-77	nuclear factor kappa B subunit 1	Homo sapiens	122-130	
23844176-8	2013	The interaction of NF-kappaB p50 subunit and Ni(2+) ions was examined by Ni(2+)-column pull down assay.	Nickel(2+)	45-51	nuclear factor kappa B subunit 1	Homo sapiens	19-32	
23844176-8	2013	The interaction of NF-kappaB p50 subunit and Ni(2+) ions was examined by Ni(2+)-column pull down assay.	Nickel(2+)	73-79	nuclear factor kappa B subunit 1	Homo sapiens	19-32	
23844176-12	2013	As IL-8 reduction was observed in a transcriptional level, we performed the luciferase assay and the data indicated that Ni(2+) ions reduced the NF-kappaB activity.	Nickel(2+)	121-127	nuclear factor kappa B subunit 1	Homo sapiens	145-154	
23844176-13	2013	Measurement of p50 subunit in the nucleus and the immunofluorescence staining revealed that the inhibitory effect of Ni(2+) ions was attributed to the prevention of p50 subunit accumulation to the nucleus.	Nickel(2+)	117-123	nuclear factor kappa B subunit 1	Homo sapiens	15-18	
23844176-13	2013	Measurement of p50 subunit in the nucleus and the immunofluorescence staining revealed that the inhibitory effect of Ni(2+) ions was attributed to the prevention of p50 subunit accumulation to the nucleus.	Nickel(2+)	117-123	nuclear factor kappa B subunit 1	Homo sapiens	165-168	
23844176-14	2013	By Ni(2+)-column pull down assay, Ni(2+) ions were shown to interact directly with His cluster in the N-terminus of p50 subunit.	Nickel(2+)	3-9	nuclear factor kappa B subunit 1	Homo sapiens	116-119	
23844176-14	2013	By Ni(2+)-column pull down assay, Ni(2+) ions were shown to interact directly with His cluster in the N-terminus of p50 subunit.	Nickel(2+)	34-40	nuclear factor kappa B subunit 1	Homo sapiens	116-119	
23844176-15	2013	The inhibitory effect of Ni(2+) ions was reverted in the transfectant expressing the His cluster-deleted p50 mutant.	Nickel(2+)	25-31	nuclear factor kappa B subunit 1	Homo sapiens	105-108	
23844176-17	2013	CONCLUSIONS: Taken together, inhibition of NF-kappaB activity by Ni(2+) ion might be a novel therapeutic strategy for the treatment of oral cancer.	Nickel(2+)	65-71	nuclear factor kappa B subunit 1	Homo sapiens	43-52	
22287454-0	2012	Ni(II) alters the NFkappaB signaling pathway in monocytic cells.	Nickel(2+)	0-6	nuclear factor kappa B subunit 1	Homo sapiens	18-26	
22287454-4	2012	Because inflammatory cytokine secretion is regulated in part by the NFkappaB signaling pathway, our goal in the current work was to determine whether Ni(II) altered cellular levels or nuclear localization of NFkappaB-family subtypes.	Nickel(2+)	150-156	nuclear factor kappa B subunit 1	Homo sapiens	208-216	
22287454-8	2012	Our results suggest that Ni(II) may increase inflammatory cytokine secretion by increasing nuclear localization of some NFkappaB subtypes.	Nickel(2+)	25-31	nuclear factor kappa B subunit 1	Homo sapiens	120-128	
16806455-2	2006	Recent data show that Ni(II) at concentrations of 10-50 microM amplifies lipopolysaccharide-triggered, NFkappaB-mediated cytokine secretion from monocytes.	Nickel(2+)	22-28	nuclear factor kappa B subunit 1	Homo sapiens	103-111	
16806455-5	2006	Our results show that Ni(II) increased (by 1-2 fold) whole-cell Nrf2 levels and nuclear translocation of Nrf2, and amplified lipopolysaccharide (LPS)-induction of Nrf2 (by 3-5 fold), but had no detectable effect on the initial activation or nuclear translocation of NFkappaB.	Nickel(2+)	22-28	nuclear factor kappa B subunit 1	Homo sapiens	266-274	
16806455-6	2006	Because Nrf2 target gene products are known regulators of NFkappaB nuclear activity, our results suggest that Ni(II) may affect cytokine secretion indirectly via modulation of the Nrf2 pathway.	Nickel(2+)	110-116	nuclear factor kappa B subunit 1	Homo sapiens	58-66