PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32438315-5 2020 The endogenous reduction of mc-COX2 can affect mitochondrial functions, suppress cell proliferation, and induce cell apoptosis. Methylcholanthrene 28-30 mitochondrially encoded cytochrome c oxidase II Homo sapiens 31-35 32438315-8 2020 We also screened and tested several chemical compounds and small-molecule inhibitors that can decrease the generation of mc-COX2. Methylcholanthrene 121-123 mitochondrially encoded cytochrome c oxidase II Homo sapiens 124-128 32438315-9 2020 It was found that the silencing of mc-COX2 in CLL cells strengthened the anti-tumor effects of drugs used in coordination. Methylcholanthrene 35-37 mitochondrially encoded cytochrome c oxidase II Homo sapiens 38-42 29117589-6 2018 Additionally, long-term exposure of MC-LR at low concentration remarkably promoted the expression of NF-kappaB p65, COX-2, iNOS, TNF-alpha, IL-1beta, and IL-6 in the cells, suggesting that long-term MC-LR exposure at low concentration can induce inflammatory reaction to HepG2 cells, which might account for MC-induced human hepatitis. Methylcholanthrene 36-38 mitochondrially encoded cytochrome c oxidase II Homo sapiens 116-121