PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15228154-8 2004 MDMA metabolism is rather complex and includes 2 main metabolic pathways: (1) O-demethylenation followed by catechol-O-methyltransferase (COMT)-catalyzed methylation and/or glucuronide/sulfate conjugation; and (2) N-dealkylation, deamination, and oxidation to the corresponding benzoic acid derivatives conjugated with glycine. Benzoic Acid 278-290 catechol-O-methyltransferase Homo sapiens 138-142 10720722-2 2000 Two overlapping pathways could be postulated: (1) demethylenation followed by catechol-O-methyl-transferase (COMT) catalyzed methylation and/or glucuronidation/sulfatation; (2) N-dealkylation, deamination and only for MDA, MDMA, MDE oxidation to the corresponding benzoic acid derivatives conjugated with glycine. Benzoic Acid 264-276 catechol-O-methyltransferase Homo sapiens 78-107 10720722-2 2000 Two overlapping pathways could be postulated: (1) demethylenation followed by catechol-O-methyl-transferase (COMT) catalyzed methylation and/or glucuronidation/sulfatation; (2) N-dealkylation, deamination and only for MDA, MDMA, MDE oxidation to the corresponding benzoic acid derivatives conjugated with glycine. Benzoic Acid 264-276 catechol-O-methyltransferase Homo sapiens 109-113