PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15749705-10	2005	Without resveratrol, the coumarin of p53-AMC peptide is solvent-exposed and makes no significant contacts with SIRT1.	coumarin	25-33	tumor protein p53	Homo sapiens	37-40	
32578917-0	2020	A synthetic coumarin derivative (4-flourophenylacetamide-acetyl coumarin) impedes cell cycle at G0/G1 stage, induces apoptosis, and inhibits metastasis via ROS-mediated p53 and AKT signaling pathways in A549 cells.	coumarin	12-20	tumor protein p53	Homo sapiens	169-172	
14634213-4	2003	We now show that, like dicoumarol, several other coumarin and flavone inhibitors of NQO1 activity, which compete with NAD(P)H for binding to NQO1, induced ubiquitin-independent p53 degradation and inhibited wild-type p53-mediated apoptosis.	coumarin	49-57	tumor protein p53	Homo sapiens	177-180	
14634213-4	2003	We now show that, like dicoumarol, several other coumarin and flavone inhibitors of NQO1 activity, which compete with NAD(P)H for binding to NQO1, induced ubiquitin-independent p53 degradation and inhibited wild-type p53-mediated apoptosis.	coumarin	49-57	tumor protein p53	Homo sapiens	217-220	
31923958-2	2020	To this end, we constructed a novel UV-light cross-linked and pH de-cross-linked coumarin-decorated cationic copolymer functionalized mesoporous silica nanoparticles (MSN) for co-delivery of chemotherapeutic agent 5-FU and tumor suppresser p53 gene.	coumarin	81-89	tumor protein p53	Homo sapiens	240-243	
28349922-0	2017	Coumarin-chalcone hybrid instigates DNA damage by minor groove binding and stabilizes p53 through post translational modifications.	coumarin	0-8	tumor protein p53	Homo sapiens	86-89