PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22302044-5 2012 Nevertheless, pretreatment of cells with 10058-F4, a specific inhibitor of c-Myc, almost eliminated the nicotinamide-induced radiosensitive effect. Niacinamide 104-116 MYC proto-oncogene, bHLH transcription factor Homo sapiens 75-80 22302044-7 2012 In contrast, nicotinamide attenuated c-Myc protein degradation induced by radiation under hypoxia through inhibition of SirT1 deacetylase activity. Niacinamide 13-25 MYC proto-oncogene, bHLH transcription factor Homo sapiens 37-42 22028816-10 2011 CONCLUSIONS/SIGNIFICANCE: This study demonstrates that nicotinamide plays an important role as a chemo-preventive and therapeutic agent in bladder cancer through the regulation of the Myc oncogenic signature. Niacinamide 55-67 MYC proto-oncogene, bHLH transcription factor Homo sapiens 184-187 1660277-3 1991 The amplified catalase and c-myc genes in HP100-1 cells were not decreased by treatment of the cells with inhibitors of poly(ADP-Ribose) polymerase, such as nicotinamide and benzamide. Niacinamide 157-169 MYC proto-oncogene, bHLH transcription factor Homo sapiens 27-32 18323656-3 2008 Nicotinamide and nicotinamide N-oxide drastically decreased c-myc expression, but isonicotinic acid had no effect, suggesting that these compounds differentiate HL-60 to granulocytes through different pathways. Niacinamide 0-12 MYC proto-oncogene, bHLH transcription factor Homo sapiens 60-65 14716882-1 2003 To explore the preparation method of liposome-mediated 99m-technetium-labeled antisense oligonucleotides of c-myc mRNA and lay foundations for antisense imaging and treatment, antisense oligonucleotides (DNA) with 15 bases and di-functional chelate, hydrazino nicotinamide derivatives, were synthesized. Niacinamide 260-272 MYC proto-oncogene, bHLH transcription factor Homo sapiens 108-113 8136711-4 1993 Whereas c-myc mRNA was suppressed by nicotinamide in proportion to its ability to reduce HASMC growth, down regulation of c-myc by 3-aminobenzamide was much less than the observed antiproliferative effect. Niacinamide 37-49 MYC proto-oncogene, bHLH transcription factor Homo sapiens 8-13