PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19074821-1	2009	Vitamin B(6) is essential in all organisms, due to its requirement as a cofactor in the form of pyridoxal 5"-phosphate (PLP) for key metabolic enzymes.	Niacinamide	0-9	pyridoxal phosphatase	Homo sapiens	120-123	
25972531-1	2015	BACKGROUND: Vitamin B-6 interconversion enzymes are important for supplying pyridoxal 5"-phosphate (PLP), the co-enzyme form, to tissues.	Niacinamide	12-21	pyridoxal phosphatase	Homo sapiens	100-103	
23444286-3	2013	The apparent clearances (CL) of doxylamine and pyridoxal 5"-phosphate (PLP; the active metabolite of vitamin B(6) ) during the first-trimester pregnancy in women who participated in a Diclectin randomized trial were compared with those of healthy, adult, nonpregnant women who participated in a voluntary PK trial.	Niacinamide	101-110	pyridoxal phosphatase	Homo sapiens	71-74	
20233826-2	2010	OBJECTIVE: To conduct a systematic review with meta-analysis of prospective studies assessing the association of vitamin B(6) intake or blood levels of pyridoxal 5"-phosphate (PLP; the active form of vitamin B(6)) with risk of colorectal cancer.	Niacinamide	200-209	pyridoxal phosphatase	Homo sapiens	176-179	
23185966-1	2012	Pyridoxal-5"-phosphate (PLP) represents an active form of Vitamin B(6) that shows relatively fast imine formation with hydrazines under physiological conditions without the need of a catalyst.	Niacinamide	58-67	pyridoxal phosphatase	Homo sapiens	24-27	
21349613-14	2011	However, erythrocyte PLP concentration was positively associated with blood glucose level (r(s) = 0.88, p = 0.002) at admission in the deficient vitamin B-6 group after adjusting for age, gender, APACHE II score, diabetic history and insulin therapy.	Niacinamide	145-154	pyridoxal phosphatase	Homo sapiens	21-24	
17851041-2	2007	We hypothesized that the gene PNPO (pyridoxine 5"-phosphatase oxidase gene) might be a candidate for susceptibility to schizophrenia because PNPO encodes pyridoxamine 5"-phosphate oxidase (EC 1.4.3.5), a rate-limiting enzyme in pyridoxal 5"-phosphate (PLP, vitamin B(6)) synthesis.	Niacinamide	257-266	pyridoxal phosphatase	Homo sapiens	252-255	
18510874-4	2008	Once inside the cells, the transduced PEP-1-PLPP fusion protein was stable for 36 h. The concentration of PLP was markedly decreased by the addition of exogenous PEP-1-PLPP to media pretreated with the vitamin B(6) precursors; pyridoxine, pyridoxal kinase and pyridoxine-5"-phosphate oxidase into cells.	Niacinamide	202-211	pyridoxal phosphatase	Homo sapiens	44-47	
18510874-5	2008	The results suggest that the transduction of the PEP-1-PLPP fusion protein can be one mode of PLP level regulation, and to replenish this enzyme in the various neurological disorders related to vitamin B(6).	Niacinamide	194-203	pyridoxal phosphatase	Homo sapiens	55-58	
17851041-3	2007	PLP is a metabolically-active form of vitamin B(6) and thus, is required as a co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.	Niacinamide	38-47	pyridoxal phosphatase	Homo sapiens	0-3	
12194934-1	2002	BACKGROUND: Pyridoxal 5"-phosphate (PLP) is the biologically active form of vitamin B(6).	Niacinamide	76-85	pyridoxal phosphatase	Homo sapiens	36-39	
12662064-1	2003	The tautomeric equilibria of a series of 3-hydroxypyridine derivatives including pyridoxal-5"-phosphate (PLP), the active form of vitamin B(6), have been studied using density functional calculations (B3LYP/6-311+G//B3LYP/6-31G) in the gas phase and in different solvents.	Niacinamide	130-139	pyridoxal phosphatase	Homo sapiens	105-108	
12194934-14	2002	CONCLUSIONS: This new PLP assay is the first homogeneous, nonradioactive, vitamin B(6) diagnostic method.	Niacinamide	74-83	pyridoxal phosphatase	Homo sapiens	22-25