PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8597033-10	1996	Niacinamide primarily reduced IL-2 and IFN-gamma, while IL-10 predominantly reduced IL-1alpha and TNF-alpha.	Niacinamide	0-11	interferon gamma	Mus musculus	39-48	
7533621-14	1995	Nicotinamide, an inhibitor of poly-ADP ribosylation, abolished LPS- and IFN gamma-induced NOS activity.	Niacinamide	0-12	interferon gamma	Mus musculus	72-81	
7529748-9	1995	Niacinamide reduced iNOS mRNA levels and markedly reduced IFN-gamma induction of endothelial class II MHC surface antigen.	Niacinamide	0-11	interferon gamma	Mus musculus	58-67	
7506533-4	1994	We found that nicotinamide, an inhibitor of ADP-ribosylation, prevented NO synthase induction in RAW 264.7 cells after stimulation with interferon gamma (IFN-gamma) and lipopolysaccharide (LPS).	Niacinamide	14-26	interferon gamma	Mus musculus	136-163	
7506533-5	1994	Furthermore, the level of NO synthase mRNA was measured by Northern-blot analysis and we found that nicotinamide prevents expression of NO synthase mRNA in IFN-gamma- and LPS-stimulated cells.	Niacinamide	100-112	interferon gamma	Mus musculus	156-165	
7506533-6	1994	Nicotinamide was also found to inhibit other macrophage functions expressed in response to IFN-gamma, i.e. tumour necrosis factor secretion and the expression of the Ia antigen of the major histocompatibility complex.	Niacinamide	0-12	interferon gamma	Mus musculus	91-100	
2143488-4	1990	Niacinamide and 3-aminobenzamide, both inhibitors of ADP ribosylation and scavengers of free radicals, attenuated the class II expression induced by IFN-gamma and TNF.	Niacinamide	0-11	interferon gamma	Mus musculus	149-158	
2151129-5	1990	In a medium containing 20 mM of nicotinamide, together with IFN-gamma and TNF, specific 51Cr release was significantly reduced (12 +/- 3%, p less than 0.01).	Niacinamide	32-44	interferon gamma	Mus musculus	60-69