PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24507733-7	2014	Moreover, nicotinamide supplementation induced tissue-specific alterations in the mRNA expression of the genes encoding nicotinamide N-methyltransferase, DNA methyltransferase 1, catalase and tumour protein p53 in the placenta and fetal liver.	Niacinamide	10-22	nicotinamide N-methyltransferase	Rattus norvegicus	120-152	
1533573-1	1992	Nicotinamide (NA) and its four isomeric methyl analogs [2-, 4-, 5- and 6-methylnicotinamides (MNs)] were tested as substrates for nicotinamide N-methyltransferase (NNMT) and amine N-methyltransferase (ANMT) using rat liver, kidney, spleen and brain 9000 x g supernatant fluids as model enzyme preparations.	Niacinamide	0-12	nicotinamide N-methyltransferase	Rattus norvegicus	130-162	
34304009-2	2021	NNMT is an enzyme that catalyzes the N-methylation of the endogenous substrate nicotinamide, as well as exogenous xenobiotics.	Niacinamide	79-91	nicotinamide N-methyltransferase	Rattus norvegicus	0-4	
32298659-3	2020	Nicotinamide (NAM) acts as a substrate of visfatin and Nicotinamide N-Methyltransferase (NNMT) leading to the generation of Nicotinamide Adenine Dinucleotide (NAD) and N1-Methylnicotinamide (MNAM), respectively.	Niacinamide	0-12	nicotinamide N-methyltransferase	Rattus norvegicus	55-87	
32298659-3	2020	Nicotinamide (NAM) acts as a substrate of visfatin and Nicotinamide N-Methyltransferase (NNMT) leading to the generation of Nicotinamide Adenine Dinucleotide (NAD) and N1-Methylnicotinamide (MNAM), respectively.	Niacinamide	0-12	nicotinamide N-methyltransferase	Rattus norvegicus	89-93	
32298659-3	2020	Nicotinamide (NAM) acts as a substrate of visfatin and Nicotinamide N-Methyltransferase (NNMT) leading to the generation of Nicotinamide Adenine Dinucleotide (NAD) and N1-Methylnicotinamide (MNAM), respectively.	Niacinamide	14-17	nicotinamide N-methyltransferase	Rattus norvegicus	55-87	
32298659-3	2020	Nicotinamide (NAM) acts as a substrate of visfatin and Nicotinamide N-Methyltransferase (NNMT) leading to the generation of Nicotinamide Adenine Dinucleotide (NAD) and N1-Methylnicotinamide (MNAM), respectively.	Niacinamide	14-17	nicotinamide N-methyltransferase	Rattus norvegicus	89-93	
23768418-7	2013	Nicotinamide had gene-specific effects on the methylation of CpG sites within the promoters and the expression of hepatic genes tested that are responsible for methyl transfer reactions (nicotinamide N-methyltransferase and DNA methyltransferase 1), for homocysteine metabolism (betaine-homocysteine S-methyltransferase, methionine synthase and cystathionine beta-synthase) and for oxidative defence (catalase and tumour protein p53).	Niacinamide	0-12	nicotinamide N-methyltransferase	Rattus norvegicus	187-219	
11926289-1	2002	This study tested the hypothesis, that nicotinamide N-methyltransferase (NAMT) activity in the brain could convert nicotinamide to 1-methylnicotinamide (MNA) and by that means damage the nigro-neostriatal dopaminergic neurons.	Niacinamide	39-51	nicotinamide N-methyltransferase	Rattus norvegicus	73-77