PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2029514-0	1991	CO binding studies of engineered cytochrome P-450ds: effects of mutations at putative distal sites in the presence of polycyclic hydrocarbons.	Hydrocarbons, Cyclic	118-141	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	33-49	
26247835-2	2016	The polycyclic hydrocarbons (PAHs), pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene, were found to induce Type I binding spectra with human cytochrome P450 (P450) 2A13 and were converted to various mono- and di-oxygenated products by this enzyme.	Hydrocarbons, Cyclic	4-27	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	150-177	
8037457-1	1994	Human cytochrome P450 (P450) 1A1 is primarily an extrahepatic enzyme and is important because of its roles in the activation of polycyclic hydrocarbons and other xenobiotic chemicals.	Hydrocarbons, Cyclic	128-151	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	6-32	
711851-5	1978	AHH, a cytochrome P-450 dependent carcinogen-metabolizing enzyme appears to play an important role in the activation of polycyclic hydrocarbons into reactive moieties that can bind to DNA and that may directly induce cancer.	Hydrocarbons, Cyclic	120-143	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	7-23	
6353196-2	1983	The content and inventory of the types of cytochrome P-450 is readily modified following in vivo treatment of animals with "inducing agents" such as barbiturates, steroids and polycyclic hydrocarbons.	Hydrocarbons, Cyclic	176-199	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	42-58	
6286112-1	1982	Human colon tumor cells (cell line LS174T) retain a cytochrome P-450-containing drug metabolism system capable of hydroxylating polycyclic hydrocarbons and the anticancer drug cyclophosphamide.	Hydrocarbons, Cyclic	128-151	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	52-68	
229673-3	1979	The contribution of the native high spin species to the total cytochrome P-450 content of microsomes was calculated to be between 40% and 65% after induction with phenobarbital and polycyclic hydrocarbons, respectively.	Hydrocarbons, Cyclic	181-204	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	62-78	
17539139-7	1978	Studies of mixed function oxidases and cytochrome P-450 system in male gonads demonstrated that the presence of AHH, EH, and GSH-ST implicate activation and detoxification of polycyclic hydrocarbons.	Hydrocarbons, Cyclic	175-198	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	39-55	
4099847-0	1971	Properties of cytochrome P-450 as affected by environmental factors: qualitative changes due to administration of polycyclic hydrocarbons.	Hydrocarbons, Cyclic	114-137	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	14-30