PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22343378-7 2012 ATP synthesis inhibitor-oligomycin-treatment suppressed the cyclin D1 and cyclin B1 expression levels and blocked cell cycle progression. Oligomycins 24-34 cyclin D1 Homo sapiens 60-69 19575044-0 2009 Oligomycin induced the proteasomal degradation of cyclin D1 protein. Oligomycins 0-10 cyclin D1 Homo sapiens 50-59 19575044-1 2009 We searched for compounds that affect the cyclin D1/retinoblastoma protein pathway from the in-house natural product library using a recombinant adenovirus with the Cre/loxP-regulated cyclin D1 overexpression system, and we found that oligomycin inhibited cell growth more effectively in cyclin D1-overexpressing SW480 cells than in control SW480 cells. Oligomycins 235-245 cyclin D1 Homo sapiens 42-51 19575044-2 2009 We also found that oligomycin reduced the expression levels of cyclin D1 protein and that this reduction is, at least in part, mediated by Thr-286 phosphorylation-dependent proteasomal degradation. Oligomycins 19-29 cyclin D1 Homo sapiens 63-72