PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11007486-5 2000 The measurements also show that bound Mg.ADP.Pi, and not bound Mg.ATP, induces the myosin to adopt the prestroke states. Magnesium 38-40 myosin heavy chain 14 Homo sapiens 83-89 7811699-1 1994 In the present study, the influence of magnesium-for-calcium exchange and phosphorylation of regulatory light chain (RLC) on accessibility of myosin and heavy meromyosin alkali light chains (A1) for papain digestion was investigated. Magnesium 39-48 myosin heavy chain 14 Homo sapiens 142-148 10692332-1 2000 In an effort to test the lever arm model of force generation, the effects of replacing magnesium with calcium as the ATP-chelated divalent cation were determined for several myosin and actomyosin reactions. Magnesium 87-96 myosin heavy chain 14 Homo sapiens 174-180 7811699-3 1994 Exchange of magnesium ions bound to RLCs for calcium ions accelerates the digestion of A1 in the presence of ATP in dephosphorylated myosin, heavy meromyosin, acto-myosin and the acto-heavy meromyosin complex. Magnesium 12-21 myosin heavy chain 14 Homo sapiens 133-170 7811699-4 1994 In the absence of ATP the exchange of magnesium ions bound to RLCs for calcium ions delays the digestion of A1 in the acto-myosin complex. Magnesium 38-47 myosin heavy chain 14 Homo sapiens 123-129 8436225-3 1993 Results indicated that AChR-specific antibodies purified from MG patient serum by binding to and elution from antigen columns were found to inhibit Ca(2+)-dependent, myosin-associated ATPase activity; interestingly, this inhibition appeared to be relatively selective in that neither K+(EDTA)-dependent nor Mg(2+)-dependent ATPase activities were sensitive to antibody-mediated interference. Magnesium 307-309 myosin heavy chain 14 Homo sapiens 166-172 1835934-1 1991 The amino-terminal region of actin participates in the binding of myosin subfragment 1 (S1) during cross-bridge cycling, thereby assisting in the activation of the magnesium-dependent myosin ATPase. Magnesium 164-173 myosin heavy chain 14 Homo sapiens 66-72 1835934-1 1991 The amino-terminal region of actin participates in the binding of myosin subfragment 1 (S1) during cross-bridge cycling, thereby assisting in the activation of the magnesium-dependent myosin ATPase. Magnesium 164-173 myosin heavy chain 14 Homo sapiens 184-190 1916220-4 1991 It was found that both the exchange of bound magnesium for calcium on myosin heads and the phosphorylation of myosin regulatory light chains control the ability of myosin heads to induce, upon binding to actin, conformational changes of thin filament leading to decrease or increase of its flexibility. Magnesium 45-54 myosin heavy chain 14 Homo sapiens 70-76 1916220-2 1991 Results of studies on the modulation of skeletal muscle contraction by phosphorylation of myosin regulatory light chains and by exchange of magnesium for calcium in myosin heads were reviewed. Magnesium 140-149 myosin heavy chain 14 Homo sapiens 165-171 2480352-5 1989 Magnesium greatly enhances the binding of these antibodies to myosin, showing that the conformation of the heavy chain in the neck region changes upon divalent cation binding to the regulatory light chain. Magnesium 0-9 myosin heavy chain 14 Homo sapiens 62-68 2788460-3 1989 An LMM fragment (Mr 62,000) of myosin has been prepared which has aggregation properties that are sensitive to the presence of Mg.ATP. Magnesium 127-129 myosin heavy chain 14 Homo sapiens 31-37 2788460-7 1989 Although assembly of the rod fragment of myosin into paracrystals does not show sensitivity to Mg.ATP, assembly of intact myosin molecules to form filaments does show sensitivity to Mg.ATP. Magnesium 182-184 myosin heavy chain 14 Homo sapiens 41-47 2788460-7 1989 Although assembly of the rod fragment of myosin into paracrystals does not show sensitivity to Mg.ATP, assembly of intact myosin molecules to form filaments does show sensitivity to Mg.ATP. Magnesium 182-184 myosin heavy chain 14 Homo sapiens 122-128 2788460-9 1989 The rearrangement of the LMM rods and intact myosin molecules both induced by the presence of Mg.ATP are probably related. Magnesium 94-96 myosin heavy chain 14 Homo sapiens 45-51 3693404-6 1987 The phosphorylated myosin could be induced to form filaments by lowering the pH or by increasing the magnesium concentration to 10 mM. Magnesium 101-110 myosin heavy chain 14 Homo sapiens 19-25 3795995-7 1986 It is suggested that they could be calcium-magnesium cells, calcium adsorbed by troponin complexes on actin filaments constituting one electrode, and magnesium complexed with ATP on myosin filaments the other. Magnesium 150-159 myosin heavy chain 14 Homo sapiens 182-188 7292626-5 1981 It is established that calcium ions are specific in the myosin ATPase reaction and they accelerate considerably the decay of this complex, while magnesium ions inhibits this process. Magnesium 145-154 myosin heavy chain 14 Homo sapiens 56-62 6873060-0 1983 The role of magnesium in binding of the nucleotide polyphosphate chain to the active site of myosin subfragment-1. Magnesium 12-21 myosin heavy chain 14 Homo sapiens 93-99 6832146-0 1983 Interaction of ADP and magnesium with the active site of myosin subfragment-1 observed by reactivity changes of the critical thiols and by direct binding methods at low and high ionic strength. Magnesium 23-32 myosin heavy chain 14 Homo sapiens 57-63 7093215-1 1982 It is shown, by means of analytical ultracentrifugation, that skeletal myosin S-1 exists in the form of a monomer-dimer mixture, in rapid reversible equilibrium, sensitive to the hydrostatic pressure, the temperature, and the composition of the buffer (at least, pH, ionic strength, presence or absence of a Mg-(phosphate compound), and presence or absence of Mg2+). Magnesium 308-310 myosin heavy chain 14 Homo sapiens 71-77 7066306-0 1982 Binding of calcium and magnesium to myosin in skeletal muscle myofibrils. Magnesium 23-32 myosin heavy chain 14 Homo sapiens 36-42 4315-0 1976 Temperature-dependent change in rate-limiting step of the magnesium-stimulated ITPase of myosin. Magnesium 58-67 myosin heavy chain 14 Homo sapiens 89-95 7229020-2 1980 Evidence is presented for the requirement of an alpha, beta, gamma-tridentate complex of magnesium and ATP as the substrate for myosin. Magnesium 89-98 myosin heavy chain 14 Homo sapiens 128-134 158981-4 1979 The adenosine triphosphatase (ATPase) of the myosin is activated by potassium and calcium and it is inhibited by magnesium. Magnesium 113-122 myosin heavy chain 14 Homo sapiens 45-51 150286-3 1978 To examine whether F-monomer will enhance the magnesium-activated myosin adenosine triphosphatase (Mg2+-ATPase) as much as F-actin, the ability of partially polymerized actin populations at equilibrium to activate the Mg2+-ATPase of heavy meromyosin was investigated. Magnesium 46-55 myosin heavy chain 14 Homo sapiens 66-72 4281653-0 1974 The characterization of myosin-product complexes and of product-release steps during the magnesium ion-dependent adenosine triphosphatase reaction. Magnesium 89-98 myosin heavy chain 14 Homo sapiens 24-30 125748-5 1975 NEM-modified myosin B ATPase exhibited a shift of the KCL dependence curve to high concentration, a shift of the maximum activation of ATPase activity to high Mg ion concentration and a suppression of substrate inhibition at high substrate concentrations. Magnesium 159-161 myosin heavy chain 14 Homo sapiens 13-19 4272702-2 1973 The stability of the chelate structure results in marked inhibition of the myosin ATPase in the presence of millimolar magnesium ion. Magnesium 119-128 myosin heavy chain 14 Homo sapiens 75-81 4282251-0 1974 [Study of the magnesium inhibition of the myosin ATPase reaction]. Magnesium 14-23 myosin heavy chain 14 Homo sapiens 42-48 4276179-4 1974 The highly purified myosin forms filaments up to 2.5 microm long in the presence of 5 mM magnesium and 0.05 M KCl. Magnesium 89-98 myosin heavy chain 14 Homo sapiens 20-26 4368532-1 1974 Evidence for change in rate limiting step of the magnesium stimulated ITPase of myosin. Magnesium 49-58 myosin heavy chain 14 Homo sapiens 80-86 4309596-0 1969 The effects of calcium and magnesium ions on the adenosine triphosphatase and inosine triphosphatase activities of myosin A. Magnesium 27-36 myosin heavy chain 14 Homo sapiens 115-121 13436432-0 1957 The effect of monovalent salts on the acceleration of myosin B ATPase by magnesium. Magnesium 73-82 myosin heavy chain 14 Homo sapiens 54-60 4222377-1 1966 In the absence of magnesium ion, the addition of actin to myosin in a 1 :4 ratio has a strong inhibitory effect on the adenosine triphosphatase activity, in contrast to the well-known activating effect of actin in the presence of magnesium ion. Magnesium 230-239 myosin heavy chain 14 Homo sapiens 58-64 13796546-0 1960 [Polyelectrolytes as interaction inhibitors and the importance of Ca and Mg for actin-myosin interaction]. Magnesium 73-75 myosin heavy chain 14 Homo sapiens 86-92 13341481-0 1956 [Affinity of myosin for magnesium in the formation of actomyosinic reticulum]. Magnesium 24-33 myosin heavy chain 14 Homo sapiens 13-19 19873507-14 1947 It is shown that in the muscle the myosin-ATPase is most probably also subjected to the inhibitory action of the Mg ions. Magnesium 113-115 myosin heavy chain 14 Homo sapiens 35-41 14923884-0 1952 Effect of calcium, magnesium and pH on adenosinetriphosphatase activity of myosin B threads. Magnesium 19-28 myosin heavy chain 14 Homo sapiens 75-81 18904759-7 1948 The recovery effect is inhibited by Mg, activated by Ca, in accordance with the effect of these ions on the activity of myosin-ATPase. Magnesium 36-38 myosin heavy chain 14 Homo sapiens 120-126 33481593-0 2021 Step-Wise Hydration of Magnesium by Four Water Molecules Precedes Phosphate Release in a Myosin Motor. Magnesium 23-32 myosin heavy chain 14 Homo sapiens 89-95 27192824-0 2016 [Magnetic Magnesium Isotope Accelerates ATP Hydrolysis Catalyzed by Myosin]. Magnesium 10-19 myosin heavy chain 14 Homo sapiens 68-74 27192824-1 2016 In this paper, we present the results of experimental studies on the influence of different magnesium isotopes, the magnetic 25Mg and nonmagnetic 24Mg and 26Mg on ATP activity of the isolated myosin subfragment-1. Magnesium 92-101 myosin heavy chain 14 Homo sapiens 192-198 15579901-4 2005 We have addressed this issue by examining how magnesium regulates the kinetics of ADP release from myosin V and actomyosin V. Our data support a model in which actin accelerates the release of ADP from myosin V by reducing the magnesium affinity of a myosin V-MgADP intermediate. Magnesium 46-55 myosin heavy chain 14 Homo sapiens 99-105 26591059-4 2015 Structures formed by actin polypeptide chain constantly form complexes with their partners (chaperones Hsp70, prefoldin and chaperonin CCT in folding process, with an Mg ion and ATP in the native state, with numerous actin-binding proteins during the formation and functioning of the cell cytoskeleton, with myosin and other proteins of the muscle contraction in the muscle cells). Magnesium 167-169 myosin heavy chain 14 Homo sapiens 308-314 25006251-0 2014 Magnesium modulates actin binding and ADP release in myosin motors. Magnesium 0-9 myosin heavy chain 14 Homo sapiens 53-59 15952789-10 2005 The data provide evidence for multiple myosin-ADP and actomyosin-ADP states and establish a kinetic and thermodynamic framework for defining the magnesium-dependent coupling between the actin and nucleotide binding sites of myosin. Magnesium 145-154 myosin heavy chain 14 Homo sapiens 39-45 15952789-10 2005 The data provide evidence for multiple myosin-ADP and actomyosin-ADP states and establish a kinetic and thermodynamic framework for defining the magnesium-dependent coupling between the actin and nucleotide binding sites of myosin. Magnesium 145-154 myosin heavy chain 14 Homo sapiens 58-64