PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16473957-0	2006	Cardiac fibrogenesis in magnesium deficiency: a role for circulating angiotensin II and aldosterone.	Magnesium	24-33	angiotensinogen	Rattus norvegicus	69-83	
16473957-7	2006	Circulating and cardiac tissue levels of angiotensin II were significantly elevated in magnesium-deficient animals (67.6% and 93.1%, respectively, vs. control).	Magnesium	87-96	angiotensinogen	Rattus norvegicus	41-55	
16473957-9	2006	Furthermore, preliminary experiments in vivo using enalapril supported a role for angiotensin II in magnesium deficiency.	Magnesium	100-109	angiotensinogen	Rattus norvegicus	82-96	
16473957-11	2006	The findings suggest that circulating angiotensin II and aldosterone may stimulate fibroblast activity and contribute to a fibrogenic response in the heart in magnesium deficiency.	Magnesium	159-168	angiotensinogen	Rattus norvegicus	38-52	
15662226-0	2005	Magnesium supplementation prevents angiotensin II-induced myocardial damage and CTGF overexpression.	Magnesium	0-9	angiotensinogen	Rattus norvegicus	35-49	
15662226-2	2005	Recent studies provide evidence that Ang II mobilizes intracellular Mg through AT1 receptor-mediated pathways.	Magnesium	68-70	angiotensinogen	Rattus norvegicus	37-43	
15662226-3	2005	We tested the hypothesis of whether magnesium supplementation prevents Ang II-induced myocardial damage and induction of the profibrotic connective tissue growth factor (CTGF).	Magnesium	36-45	angiotensinogen	Rattus norvegicus	71-77	
15662226-10	2005	Magnesium supplementation prevented Ang II-induced myocardial CTGF overexpression (P < 0.05).	Magnesium	0-9	angiotensinogen	Rattus norvegicus	36-42	
12569264-13	2003	CONCLUSIONS: Our data demonstrate that inhibitors of Na -dependent Mg transport attenuate development of hypertension in rats infused with Ang II.	Magnesium	67-69	angiotensinogen	Rattus norvegicus	139-145	
12569264-14	2003	These findings suggest a possible role for Na /Mg exchange activity in the pathogenesis of Ang II-dependent hypertension.	Magnesium	47-49	angiotensinogen	Rattus norvegicus	91-97	
2214606-8	1990	Without magnesium 80% of the cells contracted upon addition of angiotensin II.	Magnesium	8-17	angiotensinogen	Rattus norvegicus	63-77	
8798689-0	1996	Angiotensin II and vasopressin modulate intracellular free magnesium in vascular smooth muscle cells through Na+-dependent protein kinase C pathways.	Magnesium	59-68	angiotensinogen	Rattus norvegicus	0-14	
7722684-5	1995	The blood pressure-lowering effect of magnesium supplementation in DOCA-salt hypertensive rats was associated with a lower in vivo cardiovascular reactivity to norepinephrine and angiotensin II.	Magnesium	38-47	angiotensinogen	Rattus norvegicus	179-193	
12569264-4	2003	To verify that Ang II directly influences Na -dependent Mg exchange, in-vitro studies were performed in vascular smooth muscle cells (VSMCs) derived from mesenteric arteries.	Magnesium	56-58	angiotensinogen	Rattus norvegicus	15-21	
12569264-9	2003	Platelet intracellular free Mg concentration was reduced and platelet intracellular free Na concentration was increased in the Ang II group compared with control and treated groups (P < 0.01).	Magnesium	28-30	angiotensinogen	Rattus norvegicus	127-133	
8563701-7	1995	Although there was no difference in excretion of calcium, magnesium and phosphate between the two kidneys under basal conditions, infusion of ANG II or PE induced hypercalciuria, hypermagnesiuria and hyperphosphaturia in the right kidney which was exposed to the increased arterial pressure.	Magnesium	58-67	angiotensinogen	Rattus norvegicus	142-148	
2196065-0	1990	Effects of magnesium on changes in blood pressure and plasma aldosterone induced by angiotensin II.	Magnesium	11-20	angiotensinogen	Rattus norvegicus	84-98	
2196065-1	1990	This study examined the effects of magnesium on changes in blood pressure and plasma aldosterone concentration (PAC) elicited by angiotensin II in rats.	Magnesium	35-44	angiotensinogen	Rattus norvegicus	129-143	
2196065-4	1990	These effects of magnesium were abolished when endogenous angiotensin II was suppressed by the administration of captopril, an angiotensin converting enzyme inhibitor.	Magnesium	17-26	angiotensinogen	Rattus norvegicus	58-72	
2998811-5	1985	Calcium and magnesium ions (0-10 mM) increased agonist binding and decreased antagonist binding to adrenal and uterine angiotensin II receptors, an effect mediated by changes in both affinity and number of receptors for the two peptides.	Magnesium	12-21	angiotensinogen	Rattus norvegicus	119-133	
23526071-0	2013	Additional antihypertensive effect of magnesium supplementation with an angiotensin II receptor blocker in hypomagnesemic rats.	Magnesium	38-47	angiotensinogen	Rattus norvegicus	72-86	
23526071-3	2013	The purpose of this study was to evaluate the effect of dietary Mg supplementation on the blood pressure effects of an angiotensin II receptor blocker (ARB) in hypomagnesemic rats.	Magnesium	64-66	angiotensinogen	Rattus norvegicus	119-133