PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33995046-9	2021	In addition, CYP1A2 inactivation by individual furanocoumarin bioactive was concentration- and time-dependent involving the irreversible inhibition mechanism.	Furocoumarins	47-61	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	13-19	
33995046-12	2021	Thus, furanocoumarin bioactive metabolism in humans would result in reactive metabolite(s) formation inactivating CYP1A2 isozyme and inhibiting caffeine metabolism.	Furocoumarins	6-20	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	114-120	
34377680-0	2021	Determination of benchmark doses for linear furanocoumarin consumption associated with inhibition of cytochrome P450 1A2 isoenzyme activity in healthy human adults.	Furocoumarins	44-58	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	101-120	
34377680-4	2021	The first objective was to verify if the potencies of the three furanocoumarins are additive towards the inhibition of CYP1A2 activity in vitro using concentration-addition and whole-mixture chemical-mixture-assessment models.	Furocoumarins	64-79	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	119-125	
21847668-0	2011	Effects of furanocoumarins from apiaceous vegetables on the catalytic activity of recombinant human cytochrome P-450 1A2.	Furocoumarins	11-26	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	100-120	
21847668-2	2011	Consumption of apiaceous vegetables (rich in furanocoumarins) inhibits CYP1A2 in humans.	Furocoumarins	45-60	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	71-77	
21847668-3	2011	Because many furanocoumarins are potent inhibitors of several CYPs, we characterized the effects of three furanocoumarins from apiaceous vegetables on human CYP1A2 (hCYP1A2).	Furocoumarins	13-28	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	157-163	
21847668-3	2011	Because many furanocoumarins are potent inhibitors of several CYPs, we characterized the effects of three furanocoumarins from apiaceous vegetables on human CYP1A2 (hCYP1A2).	Furocoumarins	13-28	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	165-172	
21847668-3	2011	Because many furanocoumarins are potent inhibitors of several CYPs, we characterized the effects of three furanocoumarins from apiaceous vegetables on human CYP1A2 (hCYP1A2).	Furocoumarins	106-121	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	157-163	
21847668-3	2011	Because many furanocoumarins are potent inhibitors of several CYPs, we characterized the effects of three furanocoumarins from apiaceous vegetables on human CYP1A2 (hCYP1A2).	Furocoumarins	106-121	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	165-172