PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24937183-0 2014 Synthesis and cytotoxic effect on cancer cell lines and macrophages of novel progesterone derivatives having an ester or a carbamate function at C-3 and C-17. Carbamates 123-132 cytokine like 1 Homo sapiens 153-157 24937183-2 2014 In the second series, both functional groups (ester and carbamate) are bound to C-17 on the pregn-4,6-diene-3,20-dione scaffold (13a-e and 14a-e). Carbamates 56-65 cytokine like 1 Homo sapiens 80-84 24937183-4 2014 The results from this study showed that steroid 14a, having a carbamate function at C-17, was the most potent against PC-3 cell line (96.6%) while 8c and 8e showed much higher cytotoxic activity (100%) for MCF-7 cell line. Carbamates 62-71 cytokine like 1 Homo sapiens 84-88 18582482-0 2008 Synthesis of novel C17 steroidal carbamates. Carbamates 33-43 cytokine like 1 Homo sapiens 19-22 18582482-2 2008 We have exploited the reaction of 1,1"-carbonylbis(2-methylimidazole) (CBMI) with several 17beta-hydroxy androstanes to synthesize a series of novel C17 steroidal carbamates. Carbamates 163-173 cytokine like 1 Homo sapiens 149-152 18582482-7 2008 The carbamate moiety at C17 allowed tight binding of the synthesized compounds to both wild-type (wt-) and mutated AR. Carbamates 4-13 cytokine like 1 Homo sapiens 24-27 17629476-0 2007 Steroids with a carbamate function at C-17, a novel class of inhibitors for human and hamster steroid 5alpha-reductase. Carbamates 16-25 cytokine like 1 Homo sapiens 38-42