PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22309909-1 2012 It is well known that 6-nitroquipazine exhibits about 150-fold higher affinity for the serotonin transporter (SERT) than quipazine and recently we showed quipazine buspirone analogues with high to moderate SERT affinity. Quipazine 29-38 solute carrier family 6 member 4 Homo sapiens 87-108 22309909-1 2012 It is well known that 6-nitroquipazine exhibits about 150-fold higher affinity for the serotonin transporter (SERT) than quipazine and recently we showed quipazine buspirone analogues with high to moderate SERT affinity. Quipazine 29-38 solute carrier family 6 member 4 Homo sapiens 110-114 22309909-1 2012 It is well known that 6-nitroquipazine exhibits about 150-fold higher affinity for the serotonin transporter (SERT) than quipazine and recently we showed quipazine buspirone analogues with high to moderate SERT affinity. Quipazine 29-38 solute carrier family 6 member 4 Homo sapiens 206-210 22309909-3 2012 Unexpectedly, their SERT binding affinities were moderate, and much lower than that of the previously studied quipazine buspirone analogues. Quipazine 110-119 solute carrier family 6 member 4 Homo sapiens 20-24 15848758-0 2005 Structure-affinity relationship studies on arylpiperazine derivatives related to quipazine as serotonin transporter ligands. Quipazine 81-90 solute carrier family 6 member 4 Homo sapiens 94-115 15848758-2 2005 A series of quipazine derivatives, previously synthesized to probe the 5-HT(3) receptor, was evaluated for its potential interaction with serotonin transporter (SERT). Quipazine 12-21 solute carrier family 6 member 4 Homo sapiens 138-159 15848758-2 2005 A series of quipazine derivatives, previously synthesized to probe the 5-HT(3) receptor, was evaluated for its potential interaction with serotonin transporter (SERT). Quipazine 12-21 solute carrier family 6 member 4 Homo sapiens 161-165 15848758-3 2005 Some of them show nanomolar affinity for the rodent SERT comparable to or slightly higher than quipazine or N-methylquipazine. Quipazine 95-104 solute carrier family 6 member 4 Homo sapiens 52-56 15848758-5 2005 The structure-affinity relationships obtained provided information on the role of the fused benzene ring of quipazine in the interaction with the SERT binding site and on the stereoelectronic requirements for the interaction of both the heteroaromatic component and the basic moiety. Quipazine 108-117 solute carrier family 6 member 4 Homo sapiens 146-150