PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12951101-0	2003	Synthesis and biological activity of piperazine-based dual MMP-13 and TNF-alpha converting enzyme inhibitors.	Piperazine	37-47	tumor necrosis factor	Homo sapiens	70-79	
11229767-3	2001	A smaller N-substituent in the piperazine ring was required for inhibition of TNF-alpha production.	Piperazine	31-41	tumor necrosis factor	Homo sapiens	78-87	
7741042-1	1994	CGP 47969A is a novel piperazine derivative that inhibits the synthesis of inflammatory cytokines, such as interleukin-1 alpha (IL-1), IL-1 beta and tumor necrosis factor alpha (TNF), in human monocytes stimulated with lipopolysaccharide (LPS), zymosan or IL-1 itself.	Piperazine	22-32	tumor necrosis factor	Homo sapiens	149-176	
7741042-1	1994	CGP 47969A is a novel piperazine derivative that inhibits the synthesis of inflammatory cytokines, such as interleukin-1 alpha (IL-1), IL-1 beta and tumor necrosis factor alpha (TNF), in human monocytes stimulated with lipopolysaccharide (LPS), zymosan or IL-1 itself.	Piperazine	22-32	tumor necrosis factor	Homo sapiens	178-181