PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19664921-4 2009 The piperazine ring was shown to be a critical element of the HIV-1 attachment inhibiting pharmacophore, acting as a scaffold to deploy the indole glyoxamide and benzamide in a topographical relationship that complements the binding site on gp120. Piperazine 4-14 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 241-246 23748247-4 2013 We described an approach that combines molecular docking, molecular dynamics, MM-PBSA calculations and conformational analysis to rationally predict piperazine derivatives binding mode with HIV-1 gp120. Piperazine 149-159 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 196-201