PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19143029-0 2009 Piperazine-designed alpha 1A/alpha 1D-adrenoceptor blocker KMUP-1 and doxazosin provide down-regulation of androgen receptor and PSA in prostatic LNCaP cells growth and specifically in xenografts. Piperazine 0-10 androgen receptor Homo sapiens 107-124 14613328-7 2003 Relative binding affinity of the tethers bound to the targeting group for human androgen receptor were measured using a (3)H-Mibolerone competition assay and varied from 18% of nilutamide binding for the butynediol-based linear region to less than 1% for one of the piperazine derivatives. Piperazine 266-276 androgen receptor Homo sapiens 80-97