PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24898841-0 2014 Prostaglandin E2 regulation of amnion cell vascular endothelial growth factor expression: relationship with intramembranous absorption rate in fetal sheep. Dinoprostone 0-16 vascular endothelial growth factor A Ovis aries 43-77 24898841-1 2014 We hypothesized that prostaglandin E2 (PGE2) stimulates amniotic fluid transport across the amnion by upregulating vascular endothelial growth factor (VEGF) expression in amnion cells and that amniotic PGE2 concentration correlates positively with intramembranous (IM) absorption rate in fetal sheep. Dinoprostone 21-37 vascular endothelial growth factor A Ovis aries 115-149 24898841-1 2014 We hypothesized that prostaglandin E2 (PGE2) stimulates amniotic fluid transport across the amnion by upregulating vascular endothelial growth factor (VEGF) expression in amnion cells and that amniotic PGE2 concentration correlates positively with intramembranous (IM) absorption rate in fetal sheep. Dinoprostone 21-37 vascular endothelial growth factor A Ovis aries 151-155 24898841-1 2014 We hypothesized that prostaglandin E2 (PGE2) stimulates amniotic fluid transport across the amnion by upregulating vascular endothelial growth factor (VEGF) expression in amnion cells and that amniotic PGE2 concentration correlates positively with intramembranous (IM) absorption rate in fetal sheep. Dinoprostone 39-43 vascular endothelial growth factor A Ovis aries 115-149 24898841-1 2014 We hypothesized that prostaglandin E2 (PGE2) stimulates amniotic fluid transport across the amnion by upregulating vascular endothelial growth factor (VEGF) expression in amnion cells and that amniotic PGE2 concentration correlates positively with intramembranous (IM) absorption rate in fetal sheep. Dinoprostone 39-43 vascular endothelial growth factor A Ovis aries 151-155 24898841-2 2014 The effects of PGE2 at a range of concentrations on VEGF 164 and caveolin-1 gene expressions were analyzed in cultured ovine amnion cells. Dinoprostone 15-19 vascular endothelial growth factor A Ovis aries 52-56 24898841-4 2014 In ovine amnion cells, PGE2 induced dose- and time-dependent increases in VEGF 164 mRNA levels and reduced caveolin-1 mRNA and protein levels. Dinoprostone 23-27 vascular endothelial growth factor A Ovis aries 74-78 24898841-5 2014 VEGF receptor blockade abolished the caveolin-1 response, while minimally affecting the VEGF response to PGE2. Dinoprostone 105-109 vascular endothelial growth factor A Ovis aries 88-92 24898841-9 2014 Although PGE2 at micromolar concentrations induced dose-dependent responses in VEGF and caveolin-1 gene expression in cultured amnion cells consistent with a role of PGE2 in activating VEGF to mediate AF transport across the amnion, amniotic PGE2 at physiological nanomolar concentrations does not appear to regulate IM absorption rate or AF volume. Dinoprostone 9-13 vascular endothelial growth factor A Ovis aries 79-83 24898841-9 2014 Although PGE2 at micromolar concentrations induced dose-dependent responses in VEGF and caveolin-1 gene expression in cultured amnion cells consistent with a role of PGE2 in activating VEGF to mediate AF transport across the amnion, amniotic PGE2 at physiological nanomolar concentrations does not appear to regulate IM absorption rate or AF volume. Dinoprostone 9-13 vascular endothelial growth factor A Ovis aries 185-189 24898841-9 2014 Although PGE2 at micromolar concentrations induced dose-dependent responses in VEGF and caveolin-1 gene expression in cultured amnion cells consistent with a role of PGE2 in activating VEGF to mediate AF transport across the amnion, amniotic PGE2 at physiological nanomolar concentrations does not appear to regulate IM absorption rate or AF volume. Dinoprostone 166-170 vascular endothelial growth factor A Ovis aries 185-189 24898841-9 2014 Although PGE2 at micromolar concentrations induced dose-dependent responses in VEGF and caveolin-1 gene expression in cultured amnion cells consistent with a role of PGE2 in activating VEGF to mediate AF transport across the amnion, amniotic PGE2 at physiological nanomolar concentrations does not appear to regulate IM absorption rate or AF volume. Dinoprostone 166-170 vascular endothelial growth factor A Ovis aries 185-189