PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15557075-2 2004 The activity of nitric oxide synthase 2 (NOS2) and cyclooxygenase-2 (COX-2) was determined by measuring nitric oxide (NO) and prostaglandin E2 (PGE2) in bronchoalveolar lavage fluid in response to A. pleuropneumoniae in vivo. Dinoprostone 126-142 nitric oxide synthase 2 Sus scrofa 16-39 15557075-2 2004 The activity of nitric oxide synthase 2 (NOS2) and cyclooxygenase-2 (COX-2) was determined by measuring nitric oxide (NO) and prostaglandin E2 (PGE2) in bronchoalveolar lavage fluid in response to A. pleuropneumoniae in vivo. Dinoprostone 144-148 nitric oxide synthase 2 Sus scrofa 16-39 12359165-2 2002 Prostaglandin E(2) (PGE(2)) and nitric oxide (NO), derived from the enzymes cyclo-oxygenase 2 (COX2) and NO synthase 2 (NOS2), are inflammatory mediators that modulate numerous physiological and pathophysiological processes and are potentially important pharmacological targets in osteoarthritis. Dinoprostone 0-18 nitric oxide synthase 2 Sus scrofa 105-118 12359165-2 2002 Prostaglandin E(2) (PGE(2)) and nitric oxide (NO), derived from the enzymes cyclo-oxygenase 2 (COX2) and NO synthase 2 (NOS2), are inflammatory mediators that modulate numerous physiological and pathophysiological processes and are potentially important pharmacological targets in osteoarthritis. Dinoprostone 0-18 nitric oxide synthase 2 Sus scrofa 120-124 12359165-10 2002 CONCLUSION: Mechanical compression of articular cartilage increased COX2 and PGE(2) production through a NO-dependent pathway, and therefore pharmacological agents that target the NOS2 pathway in cartilage may have a significant influence on prostanoid production in the joint. Dinoprostone 77-83 nitric oxide synthase 2 Sus scrofa 180-184 14672430-9 2003 Inhibition of iNOS and COX-2 decreased NO and PGE2 production, respectively. Dinoprostone 46-50 nitric oxide synthase 2 Sus scrofa 14-18 14672430-11 2003 Nitric oxide and PGE2 production appears to be largely dependent on iNOS and COX-2 activity. Dinoprostone 17-21 nitric oxide synthase 2 Sus scrofa 68-72