PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25036966-8 2014 alpha-Lactalbumin decreased PGE2 in both plasma and colon. Dinoprostone 28-32 lactalbumin, alpha Mus musculus 0-17 25036966-9 2014 These results suggest that alpha-lactalbumin effectively inhibited colon carcinogenesis, and the inhibition may be due to the decreased PGE2 by inhibiting cyclooxygenase-2 at cancer promotion stages. Dinoprostone 136-140 lactalbumin, alpha Mus musculus 27-44 20600530-2 2010 The results indicated that commercial alpha-LA could increase prostaglandin E(2) (PGE(2)) and the expression of COX-2 via increased phosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2), p38 mitogen-activated protein kinase (MAPK) and jun N-terminal kinase (JNK), and increase nitric oxide (NO) and the expression of iNOS via the activation of ERK1/2 and JNK. Dinoprostone 62-80 lactalbumin, alpha Mus musculus 38-46 20600530-5 2010 We found to our surprise that endotoxin was there and that alpha-LA-induced NO and PGE(2) production could be suppressed by polymyxin B, a specific inhibitor of endotoxin. Dinoprostone 83-89 lactalbumin, alpha Mus musculus 59-67 7118878-2 1982 The present studies showed that the addition of prostaglandin (PG) E2 blocked the inhibitory effect of cortisol on the synthesis and accumulation of alpha-lactalbumin without affecting casein production. Dinoprostone 48-69 lactalbumin, alpha Mus musculus 149-166