PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34725110-6 2021 The Acsl4-deficient rpMACs stimulated with opZym also demonstrated an acute reduction in mRNA expression of the inflammatory cytokines, Il6, Ccl2, Nos2, and Ccl5 When Acsl4-deficient rpMACs were incubated in vitro with the TLR4 agonist, LPS, the levels of leukotriene B4 and PGE2 were also significantly decreased. Dinoprostone 275-279 acyl-CoA synthetase long-chain family member 4 Mus musculus 4-9 34725110-7 2021 In LPS-induced peritonitis, mice with myeloid-specific Acsl4 deficiency had a significant reduction in leukotriene B4 and PGE2 levels in peritoneal exudates, which was coupled with reduced infiltration of neutrophils in the peritoneal cavity as compared with wild-type mice. Dinoprostone 122-126 acyl-CoA synthetase long-chain family member 4 Mus musculus 55-60