PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15878156-0 2005 Local application of prostaglandin E2 reduces trap, calcitonin receptor and metalloproteinase-2 immunoreactivity in the rat periodontium. Dinoprostone 21-37 acid phosphatase 5, tartrate resistant Rattus norvegicus 46-50 15878156-6 2005 Those tissues treated with PGE2 at doses of 0.1 and 0.05 mg/day showed significantly reduced numbers of TRAP and CTR-positive multinucleated cells compared with matched controls (p<0.005), as well as significantly reduced numbers of TRAP- and CTR-positive multinucleated cells when compared with the placebo-treated group (p<0.001). Dinoprostone 27-31 acid phosphatase 5, tartrate resistant Rattus norvegicus 104-108 15878156-6 2005 Those tissues treated with PGE2 at doses of 0.1 and 0.05 mg/day showed significantly reduced numbers of TRAP and CTR-positive multinucleated cells compared with matched controls (p<0.005), as well as significantly reduced numbers of TRAP- and CTR-positive multinucleated cells when compared with the placebo-treated group (p<0.001). Dinoprostone 27-31 acid phosphatase 5, tartrate resistant Rattus norvegicus 236-240 15878156-8 2005 Following a 20-day period, locally released PGE2 at doses of 0.1 and 0.05 mg/day appears to affect alveolar bone resorption in the periodontium of rats, as the number of multinucleated cells expressing TRAP and CTR are significantly reduced. Dinoprostone 44-48 acid phosphatase 5, tartrate resistant Rattus norvegicus 202-206 10320820-2 1999 Previously, we have shown that SC-19220, an antagonist of the EP1 subtype of PGE receptors, inhibited tartrate-resistant acid phosphatase (TRAP)-positive cell formation by PGE2 and PTH in adherent cell cultures taken from neonatal rats. Dinoprostone 172-176 acid phosphatase 5, tartrate resistant Rattus norvegicus 102-137 10320820-2 1999 Previously, we have shown that SC-19220, an antagonist of the EP1 subtype of PGE receptors, inhibited tartrate-resistant acid phosphatase (TRAP)-positive cell formation by PGE2 and PTH in adherent cell cultures taken from neonatal rats. Dinoprostone 172-176 acid phosphatase 5, tartrate resistant Rattus norvegicus 139-143 7628405-0 1995 Parathyroid hormone increases the number of tartrate-resistant acid phosphatase-positive cells through prostaglandin E2 synthesis in adherent cell culture of neonatal rat bones. Dinoprostone 103-119 acid phosphatase 5, tartrate resistant Rattus norvegicus 44-79 7628405-4 1995 In 1-day culture, PTH (0.025-0.25 nM) and PGE2 (1 microM) increased the number of mono- and multinucleated TRAP-positive cells. Dinoprostone 42-46 acid phosphatase 5, tartrate resistant Rattus norvegicus 107-111 7628405-8 1995 Peroxides, which are produced as byproducts of PGE2 biosynthesis, were detected in the adherent cells using dichlorofluorescene and increased the number of TRAP-positive cells. Dinoprostone 47-51 acid phosphatase 5, tartrate resistant Rattus norvegicus 156-160 7628405-10 1995 These findings showed that PTH, through its effects on PGE2 synthesis and the subsequent reactions, induced the step at which TRAP is expressed, possibly during the differentiation of osteoclasts. Dinoprostone 55-59 acid phosphatase 5, tartrate resistant Rattus norvegicus 126-130