PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31301566-4	2019	The reduction of PGE2, NO, and ROS was also observed, together with the suppression of NF-kappaB, IKK, and IkappaBalpha phosphorylation.	Dinoprostone	17-21	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	107-119	
15647289-4	2005	RANKL-induced degradation of I kappa B alpha and phosphorylation of p38 MAPK and c-Jun N-terminal kinase in RAW264.7 cells were up-regulated by PGE2 in a cAMP-dependent protein kinase A (PKA)-dependent manner, suggesting that EP2 and EP4 signals cross-talk with RANK signals.	Dinoprostone	144-148	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	29-44	
23317035-10	2013	PGE2, dbcAMP and 8-Cpt-cAMP induced the phosphorylation of Akt, IkappaB kinase and IkappaBalpha and the translocation of p65 to the nucleus and increased NF-kappaB dependent reporter gene activity, which was diminished by Akti.	Dinoprostone	0-4	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	83-95	
15890324-8	2004	Inhibiting IkappaBalpha blocked trauma-induced NF-kappaB activity, COX-2 expression and PGE2 production.	Dinoprostone	88-92	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	11-23	
9862429-4	1998	PGE2 and iloprost also blocked disappearance of I kappaB-alpha from cytosolic fraction and nuclear translocation of NF-kappaB subunits p50 and p65.	Dinoprostone	0-4	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	48-62