PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7687200-5 1993 In contrast, both PGE2 and PGI2 potentiated the release of IL-3 and IL-6 which both play an important role in stimulating haemopoesis after inflammation. Dinoprostone 18-22 interleukin 3 Mus musculus 59-63 8193367-9 1994 Cells proliferating in the presence of GM-CSF and IL-3 for more than 4 days showed significant release of PGE2 (> 7 ng/10(6) cells) when stimulated by AA. Dinoprostone 106-110 interleukin 3 Mus musculus 50-54 9126704-10 1997 The fact that PGE2 inhibits LT-beta and IL-3 in Th1 but not Th2 cells points to a different mechanism of regulation of the same cytokine in different subsets. Dinoprostone 14-18 interleukin 3 Mus musculus 40-44 8436811-0 1993 Effect of prostaglandin E2 (PGE2) on IL-3/granulocyte-macrophage colony-stimulating factor production by T helper cells. Dinoprostone 10-26 interleukin 3 Mus musculus 37-41 8436811-0 1993 Effect of prostaglandin E2 (PGE2) on IL-3/granulocyte-macrophage colony-stimulating factor production by T helper cells. Dinoprostone 28-32 interleukin 3 Mus musculus 37-41 8436811-3 1993 We examined the effect of PGE2 on the production of IL-3 and granulocyte-macrophage (GM)-CSF from murine Th1 and Th2 clones. Dinoprostone 26-30 interleukin 3 Mus musculus 52-56 8436811-4 1993 When the T cells were stimulated with Ag and APC, PGE2 inhibited IL-3/GM-CSF production from 3 Th1 clones and 1 Th2 clone, but enhanced production from 3 Th2 clones. Dinoprostone 50-54 interleukin 3 Mus musculus 65-69 8436811-5 1993 A more specific bioassay demonstrated that IL-3 production was differentially affected by PGE2 in the Th clones. Dinoprostone 90-94 interleukin 3 Mus musculus 43-47 8436811-6 1993 These data suggested that the effect of PGE2 on IL-3 production is dependent, not on a property of the lymphokine, but on a property of the T cell. Dinoprostone 40-44 interleukin 3 Mus musculus 48-52 8436811-12 1993 Interestingly, PGE2 enhanced IL-3/GM-CSF (and IL-3 alone in at least some cases) from cells stimulated with ionomycin alone, demonstrating that the mode of stimulation affects the PGE2-responsiveness. Dinoprostone 15-19 interleukin 3 Mus musculus 29-33 8436811-12 1993 Interestingly, PGE2 enhanced IL-3/GM-CSF (and IL-3 alone in at least some cases) from cells stimulated with ionomycin alone, demonstrating that the mode of stimulation affects the PGE2-responsiveness. Dinoprostone 15-19 interleukin 3 Mus musculus 46-50 8436811-12 1993 Interestingly, PGE2 enhanced IL-3/GM-CSF (and IL-3 alone in at least some cases) from cells stimulated with ionomycin alone, demonstrating that the mode of stimulation affects the PGE2-responsiveness. Dinoprostone 180-184 interleukin 3 Mus musculus 29-33 8436811-14 1993 In these cells, PGE2 either inhibited IL-3 and GM-CSF production or had no effect, in no case was the lymphokine production enhanced by PGE2 as it had been with ionomycin alone. Dinoprostone 16-20 interleukin 3 Mus musculus 38-42 1615762-4 1992 We found a marked reduction in basal, 1,25-(OH)2D3, and IL-3-induced production of calcitonin receptor (CTR)-positive cells and bone resorption by cyclooxygenase inhibitors, which was restored by PGE2 addition. Dinoprostone 196-200 interleukin 3 Mus musculus 56-60 2824613-16 1987 Finally, the observation that cholera toxin, prostaglandin E2, and N6,2"-O-dibutyryl adenosine 3",5"-cyclic monophosphate mimic the effects of IL-3 and GM-CSF on bone marrow cell HDC suggests an involvement of cyclic adenosine monophosphate in factor-induced histamine-producing cell-stimulating activity. Dinoprostone 45-61 interleukin 3 Mus musculus 143-147 2169925-9 1990 The data suggest that IL-3 is important in the formation of PGE2-producing cells. Dinoprostone 60-64 interleukin 3 Mus musculus 22-26 1446774-0 1992 Prostaglandin E2 (PGE2) differentially regulates the production of IL-2 and IL-3 by murine immune T-cells. Dinoprostone 0-16 interleukin 3 Mus musculus 76-80 1446774-0 1992 Prostaglandin E2 (PGE2) differentially regulates the production of IL-2 and IL-3 by murine immune T-cells. Dinoprostone 18-22 interleukin 3 Mus musculus 76-80 1446774-2 1992 In the paper, we have examined the role of prostaglandin (PGE2) production in the regulation of two cytokines, IL-2 and IL-3, which both play a key role in contact sensitivity and delayed type hypersensitivity reactions. Dinoprostone 58-62 interleukin 3 Mus musculus 120-124 1446774-4 1992 Unexpectedly, however, IL-3 levels are enhanced in the presence of the prostaglandin PGE2 and conversely, are inhibited by treatment with aspirin, a potent inhibitor of prostaglandin metabolism. Dinoprostone 85-89 interleukin 3 Mus musculus 23-27 1663144-4 1991 PGE2 inhibited IL-6-induced proliferation and potentiated the response to IL-3. Dinoprostone 0-4 interleukin 3 Mus musculus 74-78 17628861-0 2007 IL-3 is an important differentiation factor for the development of prostaglandin E2-producing macrophages between C57BL/6 and BALB/c mice. Dinoprostone 67-83 interleukin 3 Mus musculus 0-4 17628861-3 2007 There is no strain difference in PGE2 production by GM-CSF- and M-CSF-differentiated macrophages; however, IL-3-differentiated macrophages from BALB/c mice produced higher amounts of PGE2 and lower amounts of type I cytokines than cells from C57BL/6 mice. Dinoprostone 183-187 interleukin 3 Mus musculus 107-111 17628861-7 2007 These results indicate that mPGES-1-mediated PGE2 produced by macrophages regulates immune responses, and IL-3 is an important factor for the differentiation of macrophages that produce higher amounts of PGE2 through mPGES-1 activity in BALB/c mice. Dinoprostone 204-208 interleukin 3 Mus musculus 106-110 18815228-4 2008 We here investigated PGE(2)-induced adhesion of IL-3-dependent bone marrow-derived cultured mast cells (BMMCs). Dinoprostone 21-27 interleukin 3 Mus musculus 48-52