PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34303883-9	2021	CONCLUSION: Letrozole restores Delta6-desaturase mediated synthesis of the anti-inflammatory PGE1-precursor DGLA in vitro and is the first endocrine-active agent to have opposing effects on FADS1 and FADS2 catalyzed activities.	Alprostadil	93-97	fatty acid desaturase 2	Homo sapiens	37-48	
2558092-2	1989	The PGE1 deficiency is explained as the result of reduced delta-6-desaturase activity in atopic patients.	Alprostadil	4-8	fatty acid desaturase 2	Homo sapiens	58-76	
7123414-2	1982	This appears to be due to the lack of the enzyme delta-6-desaturase which converts the essential fatty acid, linoleic acid, to gamma-linolenic acid (GLA), from which PGE1 is then synthesized.	Alprostadil	166-170	fatty acid desaturase 2	Homo sapiens	49-67	
6270521-6	1981	In meat eaters or omnivores which can acquire arachidonic acid from food, the main consequences of D6D loss will be deficiencies of GLA, dihomogamma-linolenic acid (DGLA) and prostaglandin (PG) E1.	Alprostadil	175-196	fatty acid desaturase 2	Homo sapiens	99-102	
7035343-6	1981	Viruses are known to block the enzyme delta-6-desaturase necessary for PGE1 synthesis and thus depress cell-mediated immune response.	Alprostadil	71-75	fatty acid desaturase 2	Homo sapiens	38-56	
6251348-4	1980	It has been known since 1975 that transformed cells cannot make PGE1 because of loss of the delta-6-desaturase enzyme which converts linoleic acid to gamma-linolenic acid.	Alprostadil	64-68	fatty acid desaturase 2	Homo sapiens	92-110