PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2434058-3 1986 An unsuccessful suicide attempt with the widely used pesticide chlorpyrifos (0,0-diethyl-0-3,5,6,-trichloro-2-pyridyl phosphorothioate) is reported, where prior inhibition of lymphocytic NTE correlates with the delayed development of polyneuropathy. Chlorpyrifos 63-75 patatin like phospholipase domain containing 6 Homo sapiens 187-190 7531775-3 1995 Because chlorpyrifos and other OP insecticides are designed to produce acute cholinergic effects through inhibition of acetylcholinesterase (AChE) and some OP compounds can cause OP compound-induced delayed neurotoxicity (OPIDN) via chemical modification of neurotoxic esterase (neuropathy target esterase, NTE), this review focuses on the capacity of chlorpyrifos to precipitate these and other adverse neurological consequences. Chlorpyrifos 8-20 patatin like phospholipase domain containing 6 Homo sapiens 279-305 7531775-3 1995 Because chlorpyrifos and other OP insecticides are designed to produce acute cholinergic effects through inhibition of acetylcholinesterase (AChE) and some OP compounds can cause OP compound-induced delayed neurotoxicity (OPIDN) via chemical modification of neurotoxic esterase (neuropathy target esterase, NTE), this review focuses on the capacity of chlorpyrifos to precipitate these and other adverse neurological consequences. Chlorpyrifos 8-20 patatin like phospholipase domain containing 6 Homo sapiens 307-310 1711837-5 1991 Chlorpyrifos was slowly absorbed after single oral doses and the threshold of inhibition (greater than 70%) of neuropathy target esterase (NTE), the putative target for delayed neuropathy, was reached within 5-6 days. Chlorpyrifos 0-12 patatin like phospholipase domain containing 6 Homo sapiens 111-137 1711837-5 1991 Chlorpyrifos was slowly absorbed after single oral doses and the threshold of inhibition (greater than 70%) of neuropathy target esterase (NTE), the putative target for delayed neuropathy, was reached within 5-6 days. Chlorpyrifos 0-12 patatin like phospholipase domain containing 6 Homo sapiens 139-142 1711837-7 1991 In vitro studies showed that chlorpyrifos-oxon, the active metabolite of chlorpyrifos, was 10-20 times more active against AChE than against NTE, confirming the clinical observation. Chlorpyrifos 29-41 patatin like phospholipase domain containing 6 Homo sapiens 141-144