PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10328551-0	1999	Establishment of a method for mapping of N-linked oligosaccharides and its use to analyze industrially produced recombinant erythropoietin.	n-linked oligosaccharides	41-66	erythropoietin	Homo sapiens	124-138	
15820978-4	2005	Fc-Epo was secreted from NS/0 myeloma cells as about 35% high molecular weight aggregates, was unstable upon removal of N-linked oligosaccharides and showed poor pharmacokinetics and little efficacy in mice.	n-linked oligosaccharides	120-145	erythropoietin	Homo sapiens	3-6	
15820978-5	2005	In contrast, a corresponding Fc-Epo(NDS) was secreted almost exclusively as a unit dimer, was relatively stable to removal of N-linked oligosaccharides, had much improved pharmacokinetic properties and had a significantly improved effect on RBC production.	n-linked oligosaccharides	126-151	erythropoietin	Homo sapiens	32-35	
15820978-5	2005	In contrast, a corresponding Fc-Epo(NDS) was secreted almost exclusively as a unit dimer, was relatively stable to removal of N-linked oligosaccharides, had much improved pharmacokinetic properties and had a significantly improved effect on RBC production.	n-linked oligosaccharides	126-151	erythropoietin	Homo sapiens	36-39	
10998266-2	2000	N-linked oligosaccharides were released from recombinant human EPO expressed in Chinese hamster ovary cells enzymatically and reduced with NaBH(4).	n-linked oligosaccharides	0-25	erythropoietin	Homo sapiens	63-66	
11027166-3	2000	In the work presented here, the effects of ammonia on EPO N-linked oligosaccharides were analyzed.	n-linked oligosaccharides	58-83	erythropoietin	Homo sapiens	54-57	
11372444-0	2000	[HPLC/ESI MS and MALDI/TOF MS analysis of microheterogeneity of the N-linked oligosaccharides of recombinant human erythropoietin].	n-linked oligosaccharides	68-93	erythropoietin	Homo sapiens	115-129	
1851001-1	1991	Controversy exists regarding the functional role of N-linked oligosaccharides in the hormone erythropoietin.	n-linked oligosaccharides	52-77	erythropoietin	Homo sapiens	93-107	
7766897-5	1995	Although Epo produced by tobacco cells was glycosylated with N-linked oligosaccharides, these carbohydrates were smaller than those of the recombinant Epo produced in mammalian cells.	n-linked oligosaccharides	61-86	erythropoietin	Homo sapiens	9-12	
1560005-2	1992	Three N-linked oligosaccharides of hEPO have been partially or fully removed to obtain N-glycan (NG) (2)-, NG(1)-, and NG(0)-hEPO carrying two, one, and no N-linked sugar chains, respectively.	n-linked oligosaccharides	6-31	erythropoietin	Homo sapiens	35-39	
9848672-6	1998	The profiles of heavily sialylated N-linked oligosaccharides derived from fetuin, recombinant human erythropoietin and kallikrein are reported and the data show that the present method produces a high resolution of the N-linked oligosaccharide profile for fingerprinting glycans derived from glycoproteins.	n-linked oligosaccharides	35-60	erythropoietin	Homo sapiens	100-114	
2550193-5	1989	The two major N-linked oligosaccharides of Namalwa EPO were fucose-containing tetraantennary and fucose-containing triantennary structures.	n-linked oligosaccharides	14-39	erythropoietin	Homo sapiens	51-54	
3179269-1	1988	The structures of the N-linked oligosaccharides of the urinary erythropoietin (u-EPO) purified from urine of aplastic anemic patients were analyzed and compared with those for recombinant erythropoietin (r-EPO) prepared with baby hamster kidney (BHK) cells.	n-linked oligosaccharides	22-47	erythropoietin	Homo sapiens	63-77	
3179269-1	1988	The structures of the N-linked oligosaccharides of the urinary erythropoietin (u-EPO) purified from urine of aplastic anemic patients were analyzed and compared with those for recombinant erythropoietin (r-EPO) prepared with baby hamster kidney (BHK) cells.	n-linked oligosaccharides	22-47	erythropoietin	Homo sapiens	81-84	
2960381-8	1987	Further removal of N-linked oligosaccharides from this Mr 23,000 hormone using N-Glycanase yielded an apo-erythropoietin (Mr 18,000) which possessed substantially reduced biological activity.	n-linked oligosaccharides	19-44	erythropoietin	Homo sapiens	106-120