PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11027166-3 2000 In the work presented here, the effects of ammonia on EPO N-linked oligosaccharides were analyzed. n-linked oligosaccharides 58-83 erythropoietin Homo sapiens 54-57 10998266-2 2000 N-linked oligosaccharides were released from recombinant human EPO expressed in Chinese hamster ovary cells enzymatically and reduced with NaBH(4). n-linked oligosaccharides 0-25 erythropoietin Homo sapiens 63-66 15820978-4 2005 Fc-Epo was secreted from NS/0 myeloma cells as about 35% high molecular weight aggregates, was unstable upon removal of N-linked oligosaccharides and showed poor pharmacokinetics and little efficacy in mice. n-linked oligosaccharides 120-145 erythropoietin Homo sapiens 3-6 15820978-5 2005 In contrast, a corresponding Fc-Epo(NDS) was secreted almost exclusively as a unit dimer, was relatively stable to removal of N-linked oligosaccharides, had much improved pharmacokinetic properties and had a significantly improved effect on RBC production. n-linked oligosaccharides 126-151 erythropoietin Homo sapiens 32-35 15820978-5 2005 In contrast, a corresponding Fc-Epo(NDS) was secreted almost exclusively as a unit dimer, was relatively stable to removal of N-linked oligosaccharides, had much improved pharmacokinetic properties and had a significantly improved effect on RBC production. n-linked oligosaccharides 126-151 erythropoietin Homo sapiens 36-39 11372444-0 2000 [HPLC/ESI MS and MALDI/TOF MS analysis of microheterogeneity of the N-linked oligosaccharides of recombinant human erythropoietin]. n-linked oligosaccharides 68-93 erythropoietin Homo sapiens 115-129 7766897-5 1995 Although Epo produced by tobacco cells was glycosylated with N-linked oligosaccharides, these carbohydrates were smaller than those of the recombinant Epo produced in mammalian cells. n-linked oligosaccharides 61-86 erythropoietin Homo sapiens 9-12 10328551-0 1999 Establishment of a method for mapping of N-linked oligosaccharides and its use to analyze industrially produced recombinant erythropoietin. n-linked oligosaccharides 41-66 erythropoietin Homo sapiens 124-138 9848672-6 1998 The profiles of heavily sialylated N-linked oligosaccharides derived from fetuin, recombinant human erythropoietin and kallikrein are reported and the data show that the present method produces a high resolution of the N-linked oligosaccharide profile for fingerprinting glycans derived from glycoproteins. n-linked oligosaccharides 35-60 erythropoietin Homo sapiens 100-114 1560005-2 1992 Three N-linked oligosaccharides of hEPO have been partially or fully removed to obtain N-glycan (NG) (2)-, NG(1)-, and NG(0)-hEPO carrying two, one, and no N-linked sugar chains, respectively. n-linked oligosaccharides 6-31 erythropoietin Homo sapiens 35-39 3179269-1 1988 The structures of the N-linked oligosaccharides of the urinary erythropoietin (u-EPO) purified from urine of aplastic anemic patients were analyzed and compared with those for recombinant erythropoietin (r-EPO) prepared with baby hamster kidney (BHK) cells. n-linked oligosaccharides 22-47 erythropoietin Homo sapiens 63-77 1851001-1 1991 Controversy exists regarding the functional role of N-linked oligosaccharides in the hormone erythropoietin. n-linked oligosaccharides 52-77 erythropoietin Homo sapiens 93-107 2550193-5 1989 The two major N-linked oligosaccharides of Namalwa EPO were fucose-containing tetraantennary and fucose-containing triantennary structures. n-linked oligosaccharides 14-39 erythropoietin Homo sapiens 51-54 2960381-8 1987 Further removal of N-linked oligosaccharides from this Mr 23,000 hormone using N-Glycanase yielded an apo-erythropoietin (Mr 18,000) which possessed substantially reduced biological activity. n-linked oligosaccharides 19-44 erythropoietin Homo sapiens 106-120 3179269-1 1988 The structures of the N-linked oligosaccharides of the urinary erythropoietin (u-EPO) purified from urine of aplastic anemic patients were analyzed and compared with those for recombinant erythropoietin (r-EPO) prepared with baby hamster kidney (BHK) cells. n-linked oligosaccharides 22-47 erythropoietin Homo sapiens 81-84