PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16603638-0 2006 Regulation of class II beta-tubulin expression by tumor suppressor p53 protein in mouse melanoma cells in response to Vinca alkaloid. Vinca Alkaloids 118-132 transformation related protein 53, pseudogene Mus musculus 67-70 16603638-2 2006 We found that Vinca alkaloid enhanced expression of class II beta-tubulin isotype (mTUBB2) in mouse B16F10 melanoma cells via alteration of the tumor suppressor p53 protein. Vinca Alkaloids 14-28 transformation related protein 53, pseudogene Mus musculus 161-164 9569030-0 1998 The role of MAP4 expression in the sensitivity to paclitaxel and resistance to vinca alkaloids in p53 mutant cells. Vinca Alkaloids 79-94 transformation related protein 53, pseudogene Mus musculus 98-101 9569030-2 1998 Whereas many drugs, including the vinca alkaloids, often become less effective when p53 is transcriptionally inactivated, several, most notably paclitaxel, may become more effective. Vinca Alkaloids 34-49 transformation related protein 53, pseudogene Mus musculus 84-87 9569030-3 1998 In studying the underlying mechanism(s), we found that increased MAP4 expression, which occurs with transcriptionally silent p53, is associated with increased sensitivity to paclitaxel and decreased sensitivity to vinca alkaloids. Vinca Alkaloids 214-229 transformation related protein 53, pseudogene Mus musculus 125-128