PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15746054-2 2005 Cytochrome P450 enzymes are primarily expressed in the liver and convert the prodrug cyclophosphamide to an active phosphoramide mustard and acrolein. Acrolein 141-149 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-15 3103627-3 1987 Our laboratory has shown that trans,trans-muconaldehyde (a possible metabolite of benzene) as well as acrolein and crotonaldehyde, when added to hepatic microsomes, decreased cytochrome P-450 (measured spectrophotometrically). Acrolein 102-110 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 175-191