PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26592470-3	2016	We first determined that flumazenil (100 nM-100 muM, IC50=~1 muM) acted as a negative modulator, reducing GABA (10 muM)-gated current in the presence of 100 nM THP (to increase receptor efficacy), assessed with whole cell patch clamp recordings of recombinant alpha4beta2delta expressed in HEK-293 cells.	Flumazenil	25-35	latexin	Homo sapiens	48-51	
26592470-3	2016	We first determined that flumazenil (100 nM-100 muM, IC50=~1 muM) acted as a negative modulator, reducing GABA (10 muM)-gated current in the presence of 100 nM THP (to increase receptor efficacy), assessed with whole cell patch clamp recordings of recombinant alpha4beta2delta expressed in HEK-293 cells.	Flumazenil	25-35	latexin	Homo sapiens	61-64	
26592470-3	2016	We first determined that flumazenil (100 nM-100 muM, IC50=~1 muM) acted as a negative modulator, reducing GABA (10 muM)-gated current in the presence of 100 nM THP (to increase receptor efficacy), assessed with whole cell patch clamp recordings of recombinant alpha4beta2delta expressed in HEK-293 cells.	Flumazenil	25-35	latexin	Homo sapiens	61-64	
26592470-5	2016	Flumazenil (10 muM) decreased surface expression of alpha4F by ~60%, while increasing its intracellular accumulation, after 48 h. Reduced surface expression of alpha4beta2delta after flumazenil treatment was confirmed by decreases in the current responses to 100 nM of the GABA agonist gaboxadol.	Flumazenil	0-10	latexin	Homo sapiens	15-18	
26592470-5	2016	Flumazenil (10 muM) decreased surface expression of alpha4F by ~60%, while increasing its intracellular accumulation, after 48 h. Reduced surface expression of alpha4beta2delta after flumazenil treatment was confirmed by decreases in the current responses to 100 nM of the GABA agonist gaboxadol.	Flumazenil	183-193	latexin	Homo sapiens	15-18