PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15572279-5 2005 Thioridazine (Ki=15 microM) was the most potent inhibitor of the rat CYP2D among the drugs studied, whose effect was more pronounced than that of the other neuroleptics tested: phenothiazines (Ki=18-23 microM), haloperidol (Ki=32 microM), sertindole (Ki=51 microM) or risperidone (Ki=165 microM). Phenothiazines 177-191 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 69-74 15572279-8 2005 After chronic treatment with the investigated neuroleptics, the decreased CYP2D activity produced by the phenothiazines was still maintained, while that caused by haloperidol diminished. Phenothiazines 105-119 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 74-79