PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31673250-1	2019	Aims: Our study was designed to investigate the usefulness of 99mTc-3PRGD2 single-photon emission computed tomography (SPECT) for noninvasively monitoring the response of integrin alphavbeta3 expression to antiangiogenic treatment with endostar and cisplatin in xenograft animals.	Cisplatin	249-258	integrin subunit alpha V	Homo sapiens	171-191	
34977030-3	2021	Using a Cal27 tongue squamous cell carcinoma model, we have previously demonstrated that de novo expression of integrin alphaVbeta3 confers resistance to several anticancer drugs (cisplatin, mitomycin C and doxorubicin) through a mechanism involving downregulation of active Src, increased cell migration and invasion.	Cisplatin	180-189	integrin subunit alpha V	Homo sapiens	111-131	
29426357-12	2018	CONCLUSIONS: Our findings suggest that inhibition of 14, 15-EET or inactivation of integrin alphavbeta3/FAK/PI3K/AKT pathway could serve as a novel approach to reverse EMT and cisplatin resistance in breast cancer cells.	Cisplatin	176-185	integrin subunit alpha V	Homo sapiens	83-103	
30375848-5	2018	FeGd-HN@Pt@LF/RGD2 can be internalized into cancer cells by integrin alphavbeta3-mediated endocytosis and then release Fe2+, Fe3+, and CDDP upon endosomal uptake and degradation.	Cisplatin	135-139	integrin subunit alpha V	Homo sapiens	60-80	
15146554-0	2004	Increased adenoviral transduction efficacy in human laryngeal carcinoma cells resistant to cisplatin is associated with increased expression of integrin alphavbeta3 and coxsackie adenovirus receptor.	Cisplatin	91-100	integrin subunit alpha V	Homo sapiens	144-198	
23140358-3	2012	Among the cell lines, the cisplatin-resistant IGROV-1/Pt1 cells expressed high levels of integrin alphaVbeta3, making them attractive to be tested in in vivo models.	Cisplatin	26-35	integrin subunit alpha V	Homo sapiens	89-109