PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18307537-7	2008	Indeed, YB-1 strongly stimulates in vitro the activity of hNTH1 toward DNA duplex probes containing oxidized bases, lesions prone to be present in cisplatin treated cells.	Cisplatin	147-156	nth like DNA glycosylase 1	Homo sapiens	58-63	
18307537-8	2008	We also observed an increase in YB-1/hNTH1 complex formation in the mammary adenocarcinoma MCF7 cell line treated with UV light and cisplatin.	Cisplatin	132-141	nth like DNA glycosylase 1	Homo sapiens	37-42	
18307537-10	2008	Accordingly, antisense RNAs against either YB-1 or hNTH1 increased cellular sensitivity to UV and cisplatin but not to mitomycin C.	Cisplatin	98-107	nth like DNA glycosylase 1	Homo sapiens	51-56	
18307537-13	2008	Finally, siRNA against hNTH1 re-established cytotoxicity in otherwise cisplatin-resistant YB-1 overexpressing MCF7 cells.	Cisplatin	70-79	nth like DNA glycosylase 1	Homo sapiens	23-28	
18307537-14	2008	These data indicate that hNTH1 is a relevant target to potentiate cisplatin cytotoxicity in YB-1 overexpressing tumor cells.	Cisplatin	66-75	nth like DNA glycosylase 1	Homo sapiens	25-30