PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23437382-0	2013	Klotho sensitizes human lung cancer cell line to cisplatin via PI3k/Akt pathway.	Cisplatin	49-58	klotho	Homo sapiens	0-6	
27661766-8	2016	Furthermore, overexpression of klotho had synergistic effects with cisplatin to inhibit the proliferation of drug-resistant lung cancer cells in a dose- and time-dependent manner.	Cisplatin	67-76	klotho	Homo sapiens	31-37	
25827069-6	2015	Klotho reduced EOC cell viability, enhanced cisplatin sensitivity, and reduced expression of mesenchymal markers.	Cisplatin	44-53	klotho	Homo sapiens	0-6	
23437382-5	2013	In our study, we for the first time demonstrated that klotho could attenuate the resistance of lung cancer to cisplatin based chemotherapy and the apoptosis of the resistant cells with klotho overexpression was markedly increased.	Cisplatin	110-119	klotho	Homo sapiens	54-60	
23437382-9	2013	These observations suggested that klotho could improve the resistance of lung cancer cells to chemotherapy and may serve as a potential target for the gene therapy of lung cancers resistant to cisplatin based chemotherapy.	Cisplatin	193-202	klotho	Homo sapiens	34-40	
22892191-0	2012	Protective effect of klotho protein against cisplatin ototoxicity in an auditory cell line.	Cisplatin	44-53	klotho	Homo sapiens	21-27	
22892191-4	2012	This study aimed to clarify the effect of klotho expression on cisplatin ototoxicity, using an auditory cell line.	Cisplatin	63-72	klotho	Homo sapiens	42-48	
22892191-8	2012	RESULTS: Klotho protein expression increased in cisplatin-treated auditory cells.	Cisplatin	48-57	klotho	Homo sapiens	9-15	
22892191-9	2012	Cells treated with both klotho protein and cisplatin showed a viability of 67.7 per cent, versus 59.4 per cent in cisplatin-treated cells.	Cisplatin	114-123	klotho	Homo sapiens	24-30	
22892191-10	2012	Klotho significantly attenuated the cisplatin-induced increase in reactive oxygen species, and increased the viability of cells with cisplatin-induced cytotoxicity.	Cisplatin	36-45	klotho	Homo sapiens	0-6	
22892191-10	2012	Klotho significantly attenuated the cisplatin-induced increase in reactive oxygen species, and increased the viability of cells with cisplatin-induced cytotoxicity.	Cisplatin	133-142	klotho	Homo sapiens	0-6	
22892191-11	2012	CONCLUSION: Klotho protein is protective against cisplatin-induced auditory cell cytotoxicity; inhibition of reactive oxygen species may be the main mechanism.	Cisplatin	49-58	klotho	Homo sapiens	12-18