PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15152941-4 2004 Other changes in glucose metabolism that may affect 2-DG as an antimetabolite were observed, including increases in glucose-6-phosphate dehydrogenase of 10-fold and 100-fold for taxol- and melphalan-resistant variants, respectively, suggesting higher pentose phosphate activity; increased glutamine utilisation and greater sensitivity to iodoacetic acid-induced depletion of ATP levels in the parent relative to the resistant variants. Melphalan 189-198 glucose-6-phosphate dehydrogenase Homo sapiens 116-149